Search T Helper/CD4+ T-Cell Epitope Database

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Displaying record number 233

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HXB2 Location	gp160(341-356) gp120(341-356) DNA(7245..7292)	gp160 Epitope Map
Author Location	gp120( IIIB)
Epitope	TLEQIVKKLREQFGNC	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	in vitro stimulation or selection
Experimental methods	Proliferation
Keywords

Notes

• Peptide TLEQIVKKLREQFGNC stimulation of PBMC from non-infected individuals in vitro was performed.
• Peptide priming does not always induce T cells that recognize whole protein.

References

Manca1995b F. Manca, D. Fenoglio, M. T. Valle, G. L. Pira, A. Kunkl, A. Ferraris, D. Saverino, F. Lancia, L. Mortara, L. Lozzi, M. Pierres, A. G. Dalgleish, and G. Lewis. Human CD4+ T Cells Can Discriminate the Molecular and Structural Context of T Epitopes of HIV gp120 and HIV p66. J. Acquir. Immune Defic. Syndr., 9:227-237, 1995. Notes: it in vitro priming with peptides often induced CD4+ T-cells that did not recognize whole protein. Priming with protein did not always induce T-cells that could be recognized in the context of the virus. PubMed ID: 7540488. Show all entries for this paper.