HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 489

Download this epitope record as JSON.

HXB2 Location gp160(405-420)
gp120(405-420)
DNA(7437..7484)
gp160 Epitope Map
Author Location Env( 1007)
Epitope SNNTVGNPIILPCRI Epitope Alignment
SNNTVGNPIILPCRI epitope logo
Species (MHC/HLA) mouse(H-2 IAb)
Immunogen vaccine
Experimental methods  
Keywords subtype comparisons, epitope processing, TCR usage

Vaccine Details

Vaccine type DNA, protein, vaccinia
Vaccine strain B clade 1007, D clade UG92005
Vaccine component gp140
Adjuvant Complete Freund's Adjuvant (CFA)

Notes

References

Surman2001 S. Surman, T. D. Lockey, K. S. Slobod, B. Jones, J. M. Riberdy, S. W. White, P. C. Doherty, and J. L. Hurwitz. Localization of CD4+ T Cell Epitope Hotspots to Exposed Strands of HIV Envelope Glycoprotein Suggests Structural Influences on Antigen Processing. Proc. Natl. Acad. Sci. U.S.A., 98(8):4587-4592, 10 Apr 2001. URL: http://www.pnas.org/cgi/content/full/98/8/4587. PubMed ID: 11287644. Show all entries for this paper.


Displaying record number 200980

Download this epitope record as JSON.

HXB2 Location gp160(405-420)
gp120(405-420)
DNA(7437..7484)
gp160 Epitope Map
Author Location Env (gp160)( 1007)
Epitope SNNTVGNPIILPCRI Epitope Alignment
SNNTVGNPIILPCRI epitope logo
Subtype B
Species (MHC/HLA) mouse(H-2b)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, Cytokine production
Keywords vaccine-induced immune responses, variant cross-reactivity, vaccine antigen design

Vaccine Details

Vaccine type DNA, protein, vaccinia
Vaccine strain B clade 1007, D clade UG92005
Vaccine component Env
Adjuvant Complete Freund's Adjuvant (CFA)

Notes

References

Zhan2004 Xiaoyan Zhan, Karen S. Slobod, Sherri Surman, Scott A. Brown, Chris Coleclough, and Julia L. Hurwitz. Minor cOmponents of a Multi-Envelope HIV Vaccine are Recognized by Type-Specific T-Helper Cells. Vaccine, 22(9-10):1206-1213, 12 Mar 2004. PubMed ID: 15003649. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health