Search T Helper/CD4+ T-Cell Epitope Database

Found 1 matching record:

Displaying record number 116

Download this epitope record as JSON.

HXB2 Location	Rev(41-56) DNA(8423..8470)	Rev Epitope Map
Author Location	Rev(41-56 HXB2)
Epitope	RRRRWRERQRQIHSIS	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

• One of four peptides that stimulates in PBLs from HIV-1+ donors both CD4+ Th cell proliferation and CTL to autologous targets incubated with peptide were stimulated.

References

Blazevic1995 V. Blazevic, A. Ranki, and K. J. E. Krohn. Helper and cytotoxic T cell responses of HIV type 1-infected individuals to synthetic peptides of HIV type 1 Rev. AIDS Res. Hum. Retroviruses, 11:1335-1342, 1995. The same set of four peptides from the Rev protein could stimulate proliferation of CD4+ cells and trigger CTL killing of autologous target cells transformed with EBV. PubMed ID: 8573390. Show all entries for this paper.