Search T Helper/CD4+ T-Cell Epitope Database

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Displaying record number 229

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HXB2 Location	gp160(327-341) gp120(327-341) DNA(7203..7247)	gp160 Epitope Map
Author Location	gp120(327-341 HXB2)
Epitope	RQAHCNISRAKWNNT	Epitope Alignment
Subtype	B
Species (MHC/HLA)	mouse(I-Ad)
Immunogen	vaccine
Experimental methods
Keywords

Vaccine Details

Notes

• The epitope defined here is the immunodominant epitope for a helper T-cell response to the gp120 vaccine in mice. Minimum epitope and MHC restriction determined for CTL clone that recognizes the N-terminal flank of the V3 loop.

References

Warren1992 A. P. Warren and D. B. Thomas. Class II (I-Ad) Restricted T-Cell Recognition of the V3 Loop Region of HIV-1 gp120. AIDS Res. Hum. Retroviruses, 8(5):559-564, May 1992. PubMed ID: 1381202. Show all entries for this paper.