HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 107

Download this epitope record as JSON.

HXB2 Location Vpr(66-80)
DNA(5754..5798)
Vpr Epitope Map
Author Location Vpr(66-80 IIIB)
Epitope QLLFIHFRIGCRHSR Epitope Alignment
QLLFIHFRIGCRHSR epitope logo
Species (MHC/HLA) mouse(H-2d)
Immunogen vaccine
Experimental methods  
Keywords  

Vaccine Details

Vaccine type peptide

Notes

References

Sarobe1994 P. Sarobe, J.-J. Lasarte, I. Prieto, A. Gullon, M.-J. Soto, P. Labarga, J. Prieto, and F. Borras-Cuesta. Induction of Neutralizing Antibodies against Human Immunodeficiency Virus Type 1 Using Synthetic Peptide Constructs Containing an Immunodominant T-Helper Cell Determinant from Vpr. J. Acquir. Immune Defic. Syndr., 7:635-640, 1994. Notes: A vpr peptide was shown to stimulate a T-cell proliferative response in 37\% of HIV+ individuals. This peptide was coupled with B-cell epitopes, and immunized mice were capable of antibody production. PubMed ID: 8207641. Show all entries for this paper.


Displaying record number 106

Download this epitope record as JSON.

HXB2 Location Vpr(66-80)
DNA(5754..5798)
Vpr Epitope Map
Author Location Vpr(66-80 IIIB)
Epitope QLLFIHFRIGCRHSR Epitope Alignment
QLLFIHFRIGCRHSR epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Sarobe1994 P. Sarobe, J.-J. Lasarte, I. Prieto, A. Gullon, M.-J. Soto, P. Labarga, J. Prieto, and F. Borras-Cuesta. Induction of Neutralizing Antibodies against Human Immunodeficiency Virus Type 1 Using Synthetic Peptide Constructs Containing an Immunodominant T-Helper Cell Determinant from Vpr. J. Acquir. Immune Defic. Syndr., 7:635-640, 1994. Notes: A vpr peptide was shown to stimulate a T-cell proliferative response in 37\% of HIV+ individuals. This peptide was coupled with B-cell epitopes, and immunized mice were capable of antibody production. PubMed ID: 8207641. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health