HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 201525

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HXB2 Location Gag(257-271)
p24(125-139)
DNA(1558..1602)
Gag Epitope Map
Author Location Gag(257-271 HXB2)
Epitope PVGEIYKRWIILGLN Epitope Alignment
PVGEIYKRWIILGLN epitope logo
Subtype B
Species (MHC/HLA) transgenic mouse(DRB1*01:01)
Immunogen vaccine
Experimental methods T-cell Elispot
Keywords vaccine-induced immune responses, dendritic cells

Vaccine Details

Vaccine type DNA prime with peptide boost, DNA
Vaccine strain B clade HXB2
Vaccine component Gag

Notes

References

Simon2010 Gregory G. Simon, Yongli Hu, Asif M. Khan, Jingshi Zhou, Jerome Salmon, Priya R. Chikhlikar, Keun-Ok Jung, Ernesto T. A. Marques, and J. Thomas August. Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice. PLoS One, 5(1):e8574, 2010. PubMed ID: 20052293. Show all entries for this paper.


Displaying record number 201526

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HXB2 Location Gag(257-271)
p24(125-139)
DNA(1558..1602)
Gag Epitope Map
Author Location Gag(257-271 HXB2)
Epitope PVGEIYKRWIILGLN Epitope Alignment
PVGEIYKRWIILGLN epitope logo
Subtype B
Species (MHC/HLA) transgenic mouse(DRB1*01:01)
Immunogen vaccine
Experimental methods T-cell Elispot
Keywords vaccine-induced immune responses, dendritic cells

Vaccine Details

Vaccine type DNA prime with peptide boost, DNA
Vaccine strain B clade HXB2
Vaccine component Gag

Notes

References

Simon2010 Gregory G. Simon, Yongli Hu, Asif M. Khan, Jingshi Zhou, Jerome Salmon, Priya R. Chikhlikar, Keun-Ok Jung, Ernesto T. A. Marques, and J. Thomas August. Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice. PLoS One, 5(1):e8574, 2010. PubMed ID: 20052293. Show all entries for this paper.


Displaying record number 201283

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HXB2 Location Gag(257-271)
p24(125-139)
DNA(1558..1602)
Gag Epitope Map
Author Location Gag(257-271 SF2)
Epitope PVGEIYKRWIILGLN Epitope Alignment
PVGEIYKRWIILGLN epitope logo
Epitope Name Peptide 65
Subtype B
Species (MHC/HLA) mouse(H-2d)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type protein
Vaccine strain B clade IIIB
Vaccine component Gag, Tat
Adjuvant Complete Freund's Adjuvant (CFA), Incomplete Freund's Adjuvant (IFA)

Notes

References

Cellini2008 Silvia Cellini, Cinzia Fortini, Eleonora Gallerani, Federica Destro, Egidio Brocca Cofano, Antonella Caputo, and Riccardo Gavioli. Identification of New HIV-1 Gag-Specific Cytotoxic T Lymphocyte Responses in BALB/c Mice. Virol. J., 5:81, 2008. PubMed ID: 18625037. Show all entries for this paper.


Displaying record number 201069

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HXB2 Location Gag(257-271)
p24(125-139)
DNA(1558..1602)
Gag Epitope Map
Author Location Gag(257-271 HXB-2)
Epitope PVGEIYKRWIILGLN Epitope Alignment
PVGEIYKRWIILGLN epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA DQB1*03:01, DQB1*06:01, DRB1*13:03, DRB1*15:02, DRB3*01:01, DRB5*01:02
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords  

Notes

References

Koeppe2006 John R. Koeppe, Thomas B. Campbell, Eric L. Rapaport, and Cara C. Wilson. HIV-1-Specific CD4+ T-Cell Responses Are Not Associated With Significant Viral Epitope Variation in Persons With Persistent Plasma Viremia. J. Acquir. Immune Defic. Syndr., 41(2):140-148, 1 Feb 2006. PubMed ID: 16394844. Show all entries for this paper.


Displaying record number 201093

Download this epitope record as JSON.

HXB2 Location Gag(257-271)
p24(125-139)
DNA(1558..1602)
Gag Epitope Map
Author Location  
Epitope PVGEIYKRWIILGLN Epitope Alignment
PVGEIYKRWIILGLN epitope logo
Epitope Name G065
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Canada
Experimental methods Flow cytometric T-cell cytokine assay, Proliferation
Keywords memory cells

Notes

References

Younes2003 Souheil-Antoine Younes, Bader Yassine-Diab, Alain R. Dumont, Mohamed-Rachid Boulassel, Zvi Grossman, Jean-Pierre Routy, and Rafick-Pierre Sékaly. HIV-1 Viremia Prevents the Establishment of Interleukin 2-Producing HIV-Specific memory CD4+ T Cells Endowed with Proliferative Capacity. J. Exp. Med., 198(12):1909-1922, 15 Dec 2003. PubMed ID: 14676302. Show all entries for this paper.


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