HIV molecular immunology database


Search T Helper/CD4+ T-Cell Epitope Database

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Displaying record number 201627

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HXB2 Location Pol(135-151)
Pol Epitope Map
Author Location Protease(79-95 M)
Epitope PTPVNIIGRNMLTQIGC Epitope Alignment
Epitope Name Protease(79-95)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*03:01; DPA1*01:03, DPB1*04:01; DPA1*03:01, DPB1*04:02
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu



Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.

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