HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 201012

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HXB2 Location Nef(176-193)
DNA(9322..9375)
Nef Epitope Map
Author Location Nef(176-193 B consensus)
Epitope PEKEVLVWKFDSRLAFHH Epitope Alignment
PEKEVLVWKFDSRLAFHH epitope logo
Subtype B
Species (MHC/HLA) human(DRB1*01:01, DRB1*04:01, DRB1*07:01, DRB1*11:01, DRB1*13:02, DRB1*15:01, DRB5*01:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining
Keywords supervised treatment interruptions (STI), rate of progression, immunodominance, acute/early infection

Notes

References

Kaufmann2004 Daniel E. Kaufmann, Paul M. Bailey, John Sidney, Bradford Wagner, Philip J. Norris, Mary N. Johnston, Lisa A. Cosimi, Marylyn M. Addo, Mathias Lichterfeld, Marcus Altfeld, Nicole Frahm, Christian Brander, Alessandro Sette, Bruce D. Walker, and Eric S. Rosenberg. Comprehensive Analysis of Human Immunodeficiency Virus Type 1-Specific CD4 Responses Reveals Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides. J. Virol., 78(9):4463-4477, May 2004. PubMed ID: 15078927. Show all entries for this paper.


Displaying record number 201647

Download this epitope record as JSON.

HXB2 Location Nef(176-193)
DNA(9322..9375)
Nef Epitope Map
Author Location Nef(176-193)
Epitope PEKEVLVWKFDSRLAFHH Epitope Alignment
PEKEVLVWKFDSRLAFHH epitope logo
Epitope Name OLP 91
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords immunodominance, novel epitope

Notes

References

Ranasinghe2012 Srinika Ranasinghe, Michael Flanders, Sam Cutler, Damien Z. Soghoian, Musie Ghebremichael, Isaiah Davis, Madelene Lindqvist, Florencia Pereyra, Bruce D. Walker, David Heckerman, and Hendrik Streeck. HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome. J. Virol., 86(1):277-283, Jan 2012. PubMed ID: 22031937. Show all entries for this paper.


Displaying record number 201866

Download this epitope record as JSON.

HXB2 Location Nef(176-193)
DNA(9322..9375)
Nef Epitope Map
Author Location Nef
Epitope PEKEVLVWKFDSRLAFHH Epitope Alignment
PEKEVLVWKFDSRLAFHH epitope logo
Epitope Name Peptide 91
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Germany, United States
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords immunodominance, acute/early infection, chronic infection

Notes

References

Schieffer2014 Miriam Schieffer, Heiko K. Jessen, Alexander F. Oster, Franco Pissani, Damien Z. Soghoian, Richard Lu, Arne B. Jessen, Carmen Zedlack, Bruce T. Schultz, Isaiah Davis, Srinika Ranasinghe, Eric S. Rosenberg, Galit Alter, Ralf R. Schumann, and Hendrik Streeck. Induction of Gag-specific CD4 T Cell Responses during Acute HIV Infection Is Associated with Improved Viral Control. J. Virol., 88(13):7357-7366, Jul 2014. PubMed ID: 24741089. Show all entries for this paper.


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