HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 201524

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HXB2 Location Gag(253-267)
p24(121-135)
DNA(1546..1590)
Gag Epitope Map
Author Location Gag(253-267 HXB2)
Epitope NPPIPVGEIYKRWII Epitope Alignment
NPPIPVGEIYKRWII epitope logo
Subtype B
Species (MHC/HLA) transgenic mouse(DRB1*01:01)
Immunogen vaccine
Experimental methods T-cell Elispot
Keywords vaccine-induced immune responses, dendritic cells

Vaccine Details

Vaccine type DNA prime with peptide boost, DNA
Vaccine strain B clade HXB2
Vaccine component Gag

Notes

References

Simon2010 Gregory G. Simon, Yongli Hu, Asif M. Khan, Jingshi Zhou, Jerome Salmon, Priya R. Chikhlikar, Keun-Ok Jung, Ernesto T. A. Marques, and J. Thomas August. Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice. PLoS One, 5(1):e8574, 2010. PubMed ID: 20052293. Show all entries for this paper.


Displaying record number 201712

Download this epitope record as JSON.

HXB2 Location Gag(253-267)
p24(121-135)
DNA(1546..1590)
Gag Epitope Map
Author Location Gag(253-267 LAI)
Epitope NPPIPVGEIYKRWII Epitope Alignment
NPPIPVGEIYKRWII epitope logo
Show epitope variants
Epitope Name Gag 253-267
Subtype B, C
Species (MHC/HLA) human
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding
Keywords vaccine-induced immune responses, variant cross-reactivity

Vaccine Details

Vaccine type lipopeptide
Vaccine strain B clade, C clade
Vaccine component Gag, Nef, Pol

Notes

References

Castelli2013 Florence Anne Castelli, Natacha Szely, Alexis Olivain, Nicoletta Casartelli, Caroline Grygar, Aurélie Schneider, Aurore Besse, Yves Levy, Olivier Schwartz, and Bernard Maillère. Hierarchy of CD4 T Cell Epitopes of the ANRS Lipo5 Synthetic Vaccine Relies on the Frequencies of Pre-Existing Peptide-Specific T Cells in Healthy Donors. J. Immunol., 190(11):5757-5763, 1 Jun 2013. PubMed ID: 23636059. Show all entries for this paper.


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