HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 201714

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HXB2 Location Gag(270-284)
p24(138-152)
DNA(1597..1641)
Gag Epitope Map
Author Location Gag(270-284 LAI)
Epitope LNKIVRMYSPTSILD Epitope Alignment
LNKIVRMYSPTSILD epitope logo
Show epitope variants
Epitope Name Gag 270-284
Subtype B, C
Species (MHC/HLA) human
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding
Keywords vaccine-induced immune responses, variant cross-reactivity

Vaccine Details

Vaccine type lipopeptide
Vaccine strain B clade, C clade
Vaccine component Gag, Nef, Pol

Notes

References

Castelli2013 Florence Anne Castelli, Natacha Szely, Alexis Olivain, Nicoletta Casartelli, Caroline Grygar, Aurélie Schneider, Aurore Besse, Yves Levy, Olivier Schwartz, and Bernard Maillère. Hierarchy of CD4 T Cell Epitopes of the ANRS Lipo5 Synthetic Vaccine Relies on the Frequencies of Pre-Existing Peptide-Specific T Cells in Healthy Donors. J. Immunol., 190(11):5757-5763, 1 Jun 2013. PubMed ID: 23636059. Show all entries for this paper.


Displaying record number 201986

Download this epitope record as JSON.

HXB2 Location Gag(270-284)
p24(138-152)
DNA(1597..1641)
Gag Epitope Map
Author Location Gag
Epitope LNKIVRMYSPTSILD Epitope Alignment
LNKIVRMYSPTSILD epitope logo
Epitope Name Gag 284
Species (MHC/HLA) human, mouse
Immunogen in vitro stimulation or selection, HIV-1 infection, vaccine
Country China
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Other
Keywords binding affinity, vaccine-induced immune responses, kinetics, vaccine antigen design

Vaccine Details

Vaccine type polyepitope, E. coli recombinant protein
Vaccine component Env, Gag, Nef, Pol

Notes

References

Shu2020 Jiayi Shu, Wei Shen, Haitao Liu, Yiqing Zhou, Jianhui Li, Yan Zhuang, Zhenghui Huang, Shigang Yin, Lubin Jiang, Yongtao Sun, Xia Jin, and Jianqing Xu. The Immunologic Dominance of an Epitope within a Rationally Designed Poly-Epitope Vaccine Is Influenced by Multiple Factors. Vaccine, 38(14):2913-2924, 23 Mar 2020. PubMed ID: 32127225. Show all entries for this paper.


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