Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 305

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HXB2 Location	gp160(593-604) gp41(82-93) DNA(8001..8036)	gp160 Epitope Map
Author Location	gp41(593-604 IIIB)
Epitope	LGIWGCSGKLIC	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

• Elicits T-cell proliferation and B cell responses, but only during the asymptomatic phase of HIV infection.

References

Bell1992 S. J. D. Bell, D. A. Cooper, B. E. Kemp, R. R. Doherty, and R. Penny. Definition of an Immunodominant T-Cell Epitope Contained in the Envelope gp41 Sequence of HIV-1. Clin. Exp. Immunol., 87:37-45, 1992. Notes: This gp41 peptide consistently elicits both T-cell blastogenic and B-cell (antibody) responses in asymptomatic HIV-seropositive individuals but not in ARC and AIDS patients. gp41 epitope: LGIWGCSGKLIC. PubMed ID: 1370773. Show all entries for this paper.

Displaying record number 201198

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HXB2 Location	gp160(593-604) gp41(82-93) DNA(8001..8036)	gp160 Epitope Map
Author Location
Epitope	LGIWGCSGKLIC	Epitope Alignment
		Show epitope variants
Subtype	B, BF, C
Species (MHC/HLA)	human
Immunogen	virus
Country	Brazil
Experimental methods
Keywords	subtype comparisons, viral fitness and reversion

Notes

• Determined the frequencies of known CD8+ and CD4+ Env epitope sequences among Brazilian HIV sequences of various subtypes.
• Present in 27/50 Brazilian sequences.

References

Queiroz2007 Artur Trancoso Lopo de Queiroz, Luciane Amorim Santos, Domingos Ramon Moreau, Tulio de Oliveira, David I. Watkins, Bernardo Galvão-Castro, and Luiz Carlos Junior Alcantara. Identification and Characterization of Previously Described Epitopes in HIV-1 Subtypes B, C, F and BF in Brazil. Braz. J. Infect. Dis., 11(1):27-30, Feb 2007. PubMed ID: 17625722. Show all entries for this paper.