HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 201739

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HXB2 Location gp160(207-224)
gp120(207-224)
DNA(6843..6896)
gp160 Epitope Map
Author Location Env
Epitope KVSFEPIPIHYCAPAGFA Epitope Alignment
KVSFEPIPIHYCAPAGFA epitope logo
Epitope Name OLP-316
Species (MHC/HLA) human(DRB1*01:01, DRB1*11:01, DRB3*01:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, HLA cross-presentation

Notes

References

Ranasinghe2013 Srinika Ranasinghe, Sam Cutler, Isaiah Davis, Richard Lu, Damien Z. Soghoian, Ying Qi, John Sidney, Gregory Kranias, Michael D. Flanders, Madelene Lindqvist, Bjorn Kuhl, Galit Alter, Steven G. Deeks, Bruce D. Walker, Xiaojiang Gao, Alessandro Sette, Mary Carrington, and Hendrik Streeck. Association of HLA-DRB1-Restricted CD4+ T Cell Responses with HIV Immune Control. Nat. Med., 19(7):930-933, Jul 2013. PubMed ID: 23793098. Show all entries for this paper.


Displaying record number 201638

Download this epitope record as JSON.

HXB2 Location gp160(207-224)
gp120(207-224)
DNA(6843..6896)
gp160 Epitope Map
Author Location gp120(207-224)
Epitope KVSFEPIPIHYCAPAGFA Epitope Alignment
KVSFEPIPIHYCAPAGFA epitope logo
Epitope Name OLP 316
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords immunodominance, novel epitope

Notes

References

Ranasinghe2012 Srinika Ranasinghe, Michael Flanders, Sam Cutler, Damien Z. Soghoian, Musie Ghebremichael, Isaiah Davis, Madelene Lindqvist, Florencia Pereyra, Bruce D. Walker, David Heckerman, and Hendrik Streeck. HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome. J. Virol., 86(1):277-283, Jan 2012. PubMed ID: 22031937. Show all entries for this paper.


Displaying record number 201871

Download this epitope record as JSON.

HXB2 Location gp160(207-224)
gp120(207-224)
DNA(6843..6896)
gp160 Epitope Map
Author Location gp120
Epitope KVSFEPIPIHYCAPAGFA Epitope Alignment
KVSFEPIPIHYCAPAGFA epitope logo
Epitope Name Peptide 316
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Germany, United States
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords immunodominance, acute/early infection, chronic infection

Notes

References

Schieffer2014 Miriam Schieffer, Heiko K. Jessen, Alexander F. Oster, Franco Pissani, Damien Z. Soghoian, Richard Lu, Arne B. Jessen, Carmen Zedlack, Bruce T. Schultz, Isaiah Davis, Srinika Ranasinghe, Eric S. Rosenberg, Galit Alter, Ralf R. Schumann, and Hendrik Streeck. Induction of Gag-specific CD4 T Cell Responses during Acute HIV Infection Is Associated with Improved Viral Control. J. Virol., 88(13):7357-7366, Jul 2014. PubMed ID: 24741089. Show all entries for this paper.


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