HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 201434

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HXB2 Location Pol(888-902)
Integrase(173-187)
DNA(4746..4790)
Pol Epitope Map
Author Location Pol(915-)
Epitope KTAVQMAVFIHNFKR Epitope Alignment
KTAVQMAVFIHNFKR epitope logo
Epitope Name Pol915
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 200939

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HXB2 Location Pol(888-902)
Integrase(173-187)
DNA(4746..4790)
Pol Epitope Map
Author Location Integrase(915-929)
Epitope KTAVQMAVFIHNFKR Epitope Alignment
KTAVQMAVFIHNFKR epitope logo
Epitope Name Pol7
Species (MHC/HLA) human(DR supermotif)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods Intracellular cytokine staining, Proliferation
Keywords supertype, rate of progression

Notes

References

Boaz2003 M. J. Boaz, A. Waters, S. Murad, P. J. Easterbrook, E. D'Sousa, C. van Wheeley, and A. Vyakarnam. CD4 Responses to Conserved HIV-1 T Helper Epitopes Show Both Negative and Positive Associations with Virus Load in Chronically Infected Subjects. Clin. Exp. Immunol., 134(3):454-463, Dec 2003. PubMed ID: 14632751. Show all entries for this paper.


Displaying record number 201724

Download this epitope record as JSON.

HXB2 Location Pol(888-902)
Integrase(173-187)
DNA(4746..4790)
Pol Epitope Map
Author Location  
Epitope KTAVQMAVFIHNFKR Epitope Alignment
KTAVQMAVFIHNFKR epitope logo
Subtype A
Species (MHC/HLA) human, mouse
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine strain A clade, B clade, C clade
Vaccine component Env, Gag, Nef, Pol, RT

Notes

References

Reguzova2015 Alena Reguzova, Denis Antonets, Larisa Karpenko, Alexander Ilyichev, Rinat Maksyutov, and Sergei Bazhan. Design and Evaluation of Optimized Artificial HIV-1 Poly-T Cell-Epitope Immunogens. PLoS One, 10(3):e0116412, 2015. PubMed ID: 25786238. Show all entries for this paper.


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