HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 201013

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HXB2 Location Nef(184-199)
DNA(9346..9393)
Nef Epitope Map
Author Location Nef(184-199 B consensus)
Epitope KFDSRLAFHHMARELH Epitope Alignment
KFDSRLAFHHMARELH epitope logo
Subtype B
Species (MHC/HLA) human(DRB1*01:01, DRB1*07:01, DRB1*11:01, DRB1*15:01, DRB5*01:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords supervised treatment interruptions (STI), immunodominance

Notes

References

Kaufmann2004 Daniel E. Kaufmann, Paul M. Bailey, John Sidney, Bradford Wagner, Philip J. Norris, Mary N. Johnston, Lisa A. Cosimi, Marylyn M. Addo, Mathias Lichterfeld, Marcus Altfeld, Nicole Frahm, Christian Brander, Alessandro Sette, Bruce D. Walker, and Eric S. Rosenberg. Comprehensive Analysis of Human Immunodeficiency Virus Type 1-Specific CD4 Responses Reveals Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides. J. Virol., 78(9):4463-4477, May 2004. PubMed ID: 15078927. Show all entries for this paper.


Displaying record number 201748

Download this epitope record as JSON.

HXB2 Location Nef(184-199)
DNA(9346..9393)
Nef Epitope Map
Author Location Nef
Epitope KFDSRLAFHHMARELH Epitope Alignment
KFDSRLAFHHMARELH epitope logo
Epitope Name OLP-92
Species (MHC/HLA) human(DRB1*03:02, DRB1*13:02, DRB1*13:03, DRB3*03:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, HLA cross-presentation

Notes

References

Ranasinghe2013 Srinika Ranasinghe, Sam Cutler, Isaiah Davis, Richard Lu, Damien Z. Soghoian, Ying Qi, John Sidney, Gregory Kranias, Michael D. Flanders, Madelene Lindqvist, Bjorn Kuhl, Galit Alter, Steven G. Deeks, Bruce D. Walker, Xiaojiang Gao, Alessandro Sette, Mary Carrington, and Hendrik Streeck. Association of HLA-DRB1-Restricted CD4+ T Cell Responses with HIV Immune Control. Nat. Med., 19(7):930-933, Jul 2013. PubMed ID: 23793098. Show all entries for this paper.


Displaying record number 201086

Download this epitope record as JSON.

HXB2 Location Nef(184-199)
DNA(9346..9393)
Nef Epitope Map
Author Location Nef(184-199)
Epitope KFDSRLAFHHMARELH Epitope Alignment
KFDSRLAFHHMARELH epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Netherlands
Experimental methods Cytokine production
Keywords  

Notes

References

Geels2006 Mark J. Geels, Christine A. Jansen, Elly Baan, Iris M. De Cuyper, Gijs J. M. van Schijndel, Hanneke Schuitemaker, Jaap Goudsmit, Georgios Pollakis, Frank Miedema, William A. Paxton, and Debbie van Baarle. CTL Escape and Increased Viremia Irrespective of HIV-Specific CD4+ T-Helper Responses in Two HIV-Infected Individuals. Virology, 345(1):209-219, 5 Feb 2006. PubMed ID: 16246391. Show all entries for this paper.


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