HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 201527

Download this epitope record as JSON.

HXB2 Location Gag(261-275)
p24(129-143)
DNA(1570..1614)
Gag Epitope Map
Author Location Gag(261-275 HXB2)
Epitope IYKRWIILGLNKIVR Epitope Alignment
IYKRWIILGLNKIVR epitope logo
Subtype B
Species (MHC/HLA) transgenic mouse(DRB1*01:01)
Immunogen vaccine
Experimental methods T-cell Elispot
Keywords vaccine-induced immune responses, dendritic cells

Vaccine Details

Vaccine type DNA prime with peptide boost, DNA
Vaccine strain B clade HXB2
Vaccine component Gag

Notes

References

Simon2010 Gregory G. Simon, Yongli Hu, Asif M. Khan, Jingshi Zhou, Jerome Salmon, Priya R. Chikhlikar, Keun-Ok Jung, Ernesto T. A. Marques, and J. Thomas August. Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice. PLoS One, 5(1):e8574, 2010. PubMed ID: 20052293. Show all entries for this paper.


Displaying record number 201075

Download this epitope record as JSON.

HXB2 Location Gag(261-275)
p24(129-143)
DNA(1570..1614)
Gag Epitope Map
Author Location Gag(261-275 HXB-2)
Epitope IYKRWIILGLNKIVR Epitope Alignment
IYKRWIILGLNKIVR epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA DQB1*03:01, DQB1*06:01, DRB1*13:03, DRB1*15:02, DRB3*01:01, DRB5*01:02
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords  

Notes

References

Koeppe2006 John R. Koeppe, Thomas B. Campbell, Eric L. Rapaport, and Cara C. Wilson. HIV-1-Specific CD4+ T-Cell Responses Are Not Associated With Significant Viral Epitope Variation in Persons With Persistent Plasma Viremia. J. Acquir. Immune Defic. Syndr., 41(2):140-148, 1 Feb 2006. PubMed ID: 16394844. Show all entries for this paper.


Displaying record number 201701

Download this epitope record as JSON.

HXB2 Location Gag(261-275)
p24(129-143)
DNA(1570..1614)
Gag Epitope Map
Author Location Gag
Epitope IYKRWIILGLNKIVR Epitope Alignment
IYKRWIILGLNKIVR epitope logo
Epitope Name Gag-IR15
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD4 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, computational epitope prediction

Notes

References

Buggert2012 Marcus Buggert, Melissa M. Norström, Chris Czarnecki, Emmanuel Tupin, Ma Luo, Katarina Gyllensten, Anders Sönnerborg, Claus Lundegaard, Ole Lund, Morten Nielsen, and Annika C. Karlsson. Characterization of HIV-Specific CD4+ T Cell Responses Against Peptides Selected with Broad Population and Pathogen Coverage. PLoS One, 7(7):e39874, 2012. PubMed ID: 22792193. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health