HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 201043

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HXB2 Location Gag(267-277)
p24(135-145)
DNA(1588..1620)
Gag Epitope Map
Author Location p24(135-145 B Consensus)
Epitope ILGLNKIVRMY Epitope Alignment
ILGLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(DRB1*04:01, DRB1*13:02, DRB1*15:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining
Keywords supervised treatment interruptions (STI), rate of progression, immunodominance, acute/early infection

Notes

References

Kaufmann2004 Daniel E. Kaufmann, Paul M. Bailey, John Sidney, Bradford Wagner, Philip J. Norris, Mary N. Johnston, Lisa A. Cosimi, Marylyn M. Addo, Mathias Lichterfeld, Marcus Altfeld, Nicole Frahm, Christian Brander, Alessandro Sette, Bruce D. Walker, and Eric S. Rosenberg. Comprehensive Analysis of Human Immunodeficiency Virus Type 1-Specific CD4 Responses Reveals Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides. J. Virol., 78(9):4463-4477, May 2004. PubMed ID: 15078927. Show all entries for this paper.


Displaying record number 201378

Download this epitope record as JSON.

HXB2 Location Gag(267-277)
p24(135-145)
DNA(1588..1620)
Gag Epitope Map
Author Location p24(135-145)
Epitope ILGLNKIVRMY Epitope Alignment
ILGLNKIVRMY epitope logo
Species (MHC/HLA) human(DRB1*04:01, DRB1*13:02, DRB1*15:01)
Immunogen vaccine
Country Russia
Experimental methods T-cell Elispot
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, virus-like particle (VLP), HIV infected-cell lysate, polyepitope
Vaccine component Env, Gag, Nef, Pol

Notes

References

Bazhan2008 Sergei I. Bazhan, Larisa I. Karpenko, Leonid R. Lebedev, Roman V. Uzhachenko, Pavel A. Belavin, Alexey M. Eroshkin, and Alexander A. Ilyichev. A Synergistic Effect of a Combined Bivalent DNA-Protein Anti-HIV-1 Vaccine Containing Multiple T- and B-Cell Epitopes of HIV-1 Proteins. Mol. Immunol., 45(3):661-669, Feb 2008. PubMed ID: 17869341. Show all entries for this paper.


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