HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 201653

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HXB2 Location Gag(269-283)
p24(137-151)
DNA(1594..1638)
Gag Epitope Map
Author Location Gag
Epitope GLNKIVRMYSPVSIL Epitope Alignment
GLNKIVRMYSPVSIL epitope logo
Epitope Name Gag-GL15
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD4 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, computational epitope prediction

Notes

References

Buggert2012 Marcus Buggert, Melissa M. Norström, Chris Czarnecki, Emmanuel Tupin, Ma Luo, Katarina Gyllensten, Anders Sönnerborg, Claus Lundegaard, Ole Lund, Morten Nielsen, and Annika C. Karlsson. Characterization of HIV-Specific CD4+ T Cell Responses Against Peptides Selected with Broad Population and Pathogen Coverage. PLoS One, 7(7):e39874, 2012. PubMed ID: 22792193. Show all entries for this paper.


Displaying record number 201889

Download this epitope record as JSON.

HXB2 Location Gag(269-283)
p24(137-151)
DNA(1594..1638)
Gag Epitope Map
Author Location Gag
Epitope GLNKIVRMYSPVSIL Epitope Alignment
GLNKIVRMYSPVSIL epitope logo
Epitope Name Gag 17
Subtype A, B
Species (MHC/HLA) human
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine strain A clade, B clade, C clade, D clade

Notes

References

Ahmed2016 Tina Ahmed, Nicola J. Borthwick, Jill Gilmour, Peter Hayes, Lucy Dorrell, and Tomáš Hanke. Control of HIV-1 Replication In Vitro by Vaccine-Induced Human CD8+ T Cells through Conserved Subdominant Pol Epitopes. Vaccine, 34(9):1215-1224, 24 Feb 2016. PubMed ID: 26784683. Show all entries for this paper.


Displaying record number 201947

Download this epitope record as JSON.

HXB2 Location Gag(269-283)
p24(137-151)
DNA(1594..1638)
Gag Epitope Map
Author Location Gag(269-283)
Epitope GLNKIVRMYSPVSIL Epitope Alignment
GLNKIVRMYSPVSIL epitope logo
Epitope Name HC017
Subtype A, B
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA VID418: A*02:01, A*24:02, B*07:02, B*27:05, C*01:02, C*07:02, DQB1*03:01, DQB1*03:03, DRB1*04:01, DRB1*07:01, DRB4
Country United Kingdom
Experimental methods CD4 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords vaccine-induced immune responses, CD4+ CTL

Vaccine Details

Vaccine type non-replicating adenovirus, polyepitope, DNA prime with modified vaccinia Ankara (MVA) boost, HIVconsv
Vaccine strain A clade, B clade, multiple epitope immunogen, C clade, D clade
Vaccine component Env, Gag, Pol, Vif, other

Notes

References

Borthwick2020 Nicola Borthwick, Sandra Silva-Arrieta, Anuska Llano, Masafumi Takiguchi, Christian Brander, and Tomáš Hanke. Novel Nested Peptide Epitopes Recognized by CD4+ T Cells Induced by HIV-1 Conserved-Region Vaccines. Vaccines, 8(1), 16 Jan 2020. PubMed ID: 31963212. Show all entries for this paper.


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