HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 1 matching record:

Displaying record number 201957

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HXB2 Location Gag(269-281)
p24(137-149)
DNA(1594..1632)
Gag Epitope Map
Author Location Gag(269-281)
Epitope GLNKIVRMYSPVS Epitope Alignment
GLNKIVRMYSPVS epitope logo
Epitope Name HC017D
Subtype A, B
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA VID418: A*02:01, A*24:02, B*07:02, B*27:05, C*01:02, C*07:02, DQB1*03:01, DQB1*03:03, DRB1*04:01, DRB1*07:01, DRB4
Country United Kingdom
Experimental methods CD4 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords vaccine-induced immune responses, CD4+ CTL

Vaccine Details

Vaccine type non-replicating adenovirus, polyepitope, DNA prime with modified vaccinia Ankara (MVA) boost, HIVconsv
Vaccine strain A clade, B clade, multiple epitope immunogen, C clade, D clade
Vaccine component Env, Gag, Pol, Vif, other

Notes

References

Borthwick2020 Nicola Borthwick, Sandra Silva-Arrieta, Anuska Llano, Masafumi Takiguchi, Christian Brander, and Tomáš Hanke. Novel Nested Peptide Epitopes Recognized by CD4+ T Cells Induced by HIV-1 Conserved-Region Vaccines. Vaccines, 8(1), 16 Jan 2020. PubMed ID: 31963212. Show all entries for this paper.


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