HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 201428

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HXB2 Location Gag(259-273)
p24(127-141)
DNA(1564..1608)
Gag Epitope Map
Author Location Gag(294-)
Epitope GEIYKRWIILGLNKI Epitope Alignment
GEIYKRWIILGLNKI epitope logo
Epitope Name Gag294
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 398

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HXB2 Location Gag(259-273)
p24(127-141)
DNA(1564..1608)
Gag Epitope Map
Author Location Gag(294-308)
Epitope GEIYKRWIILGLNKI Epitope Alignment
GEIYKRWIILGLNKI epitope logo
Epitope Name Gag 294
Species (MHC/HLA) human(DR supermotif)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons

Notes

References

Wilson2001 C. C. Wilson, B. Palmer, S. Southwood, J. Sidney, Y. Higashimoto, E. Appella, R. Chesnut, A. Sette, and B. D. Livingston. Identification and antigenicity of broadly cross-reactive and conserved human immunodeficiency virus type 1-derived helper T-lymphocyte epitopes. J. Virol., 75(9):4195-207, May 2001. URL: http://jvi.asm.org/cgi/content/full/75/9/4195. PubMed ID: 11287569. Show all entries for this paper.


Displaying record number 200935

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HXB2 Location Gag(259-273)
p24(127-141)
DNA(1564..1608)
Gag Epitope Map
Author Location p24(294-308)
Epitope GEIYKRWIILGLNKI Epitope Alignment
GEIYKRWIILGLNKI epitope logo
Epitope Name Gag2
Species (MHC/HLA) human(DR supermotif)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods Cytokine production, Proliferation
Keywords supertype, rate of progression

Notes

References

Boaz2003 M. J. Boaz, A. Waters, S. Murad, P. J. Easterbrook, E. D'Sousa, C. van Wheeley, and A. Vyakarnam. CD4 Responses to Conserved HIV-1 T Helper Epitopes Show Both Negative and Positive Associations with Virus Load in Chronically Infected Subjects. Clin. Exp. Immunol., 134(3):454-463, Dec 2003. PubMed ID: 14632751. Show all entries for this paper.


Displaying record number 201713

Download this epitope record as JSON.

HXB2 Location Gag(259-273)
p24(127-141)
DNA(1564..1608)
Gag Epitope Map
Author Location Gag(259-273 LAI)
Epitope GEIYKRWIILGLNKI Epitope Alignment
GEIYKRWIILGLNKI epitope logo
Show epitope variants
Epitope Name Gag 259-273
Subtype B, C
Species (MHC/HLA) human
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding
Keywords vaccine-induced immune responses, variant cross-reactivity

Vaccine Details

Vaccine type lipopeptide
Vaccine strain B clade, C clade
Vaccine component Gag, Nef, Pol

Notes

References

Castelli2013 Florence Anne Castelli, Natacha Szely, Alexis Olivain, Nicoletta Casartelli, Caroline Grygar, Aurélie Schneider, Aurore Besse, Yves Levy, Olivier Schwartz, and Bernard Maillère. Hierarchy of CD4 T Cell Epitopes of the ANRS Lipo5 Synthetic Vaccine Relies on the Frequencies of Pre-Existing Peptide-Specific T Cells in Healthy Donors. J. Immunol., 190(11):5757-5763, 1 Jun 2013. PubMed ID: 23636059. Show all entries for this paper.


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