HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 201631

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HXB2 Location Pol(568-582)
RT(413-427)
DNA(3786..3830)
Pol Epitope Map
Author Location Protease(413-427 M)
Epitope EWEFVNTPPLVKLWY Epitope Alignment
EWEFVNTPPLVKLWY epitope logo
Epitope Name Protease(413-427)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*02:01, DPB1*01:01; DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*04:01; DPA1*01:03, DPB1*20:01; DQA1*05:01, DQB1*02:01; DQA1*01:01, DQB1*05:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201690

Download this epitope record as JSON.

HXB2 Location Pol(568-582)
RT(413-427)
DNA(3786..3830)
Pol Epitope Map
Author Location Pol
Epitope EWEFVNTPPLVKLWY Epitope Alignment
EWEFVNTPPLVKLWY epitope logo
Epitope Name Pol-EY15
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD4 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, computational epitope prediction

Notes

References

Buggert2012 Marcus Buggert, Melissa M. Norström, Chris Czarnecki, Emmanuel Tupin, Ma Luo, Katarina Gyllensten, Anders Sönnerborg, Claus Lundegaard, Ole Lund, Morten Nielsen, and Annika C. Karlsson. Characterization of HIV-Specific CD4+ T Cell Responses Against Peptides Selected with Broad Population and Pathogen Coverage. PLoS One, 7(7):e39874, 2012. PubMed ID: 22792193. Show all entries for this paper.


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