HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 200898

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HXB2 Location Gag(167-176)
p24(35-44)
DNA(1288..1317)
Gag Epitope Map
Author Location p24( HXB2)
Epitope EVIPMFSALS Epitope Alignment
EVIPMFSALS epitope logo
Subtype B
Species (MHC/HLA) human(DR4)
Immunogen in vitro stimulation or selection
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords epitope processing, vaccine antigen design, characterizing CD8+ T cells

Notes

References

SenGupta2004 Devi SenGupta, Philip J. Norris, Todd J. Suscovich, Mina Hassan-Zahraee, Howell F. Moffett, Alicja Trocha, Rika Draenert, Philip J. R. Goulder, Robert J. Binder, Daniel L. Levey, Bruce D. Walker, Pramod K. Srivastava, and Christian Brander. Heat Shock Protein-Mediated Cross-Presentation of Exogenous HIV Antigen on HLA Class I and Class II. J. Immunol., 173(3):1987-1993, 1 Aug 2004. PubMed ID: 15265933. Show all entries for this paper.


Displaying record number 200974

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HXB2 Location Gag(167-176)
p24(35-44)
DNA(1288..1317)
Gag Epitope Map
Author Location p24(168-177 NY-5)
Epitope EVIPMFSALS Epitope Alignment
EVIPMFSALS epitope logo
Epitope Name ES10
Subtype B
Species (MHC/HLA) human(DR4)
Immunogen HIV-1 infection
Patient MHC/HLA DQ3, DQ6, DR15, DR4, DRw51, DRw53
Country United States
Experimental methods CD4 T-cell Elispot - IFNγ, Chromium-release assay, Proliferation
Keywords rate of progression, acute/early infection, early treatment, variant cross-reactivity

Notes

References

Norris2004 Philip J. Norris, Howell F. Moffett, Christian Brander, Todd M. Allen, Kristin M. O'Sullivan, Lisa A. Cosimi, Daniel E Kaufmann, Bruce D. Walker, and Eric S. Rosenberg. Fine Specificity and Cross-Clade Reactivity of HIV Type 1 Gag-Specific CD4+ T Cells. AIDS Res. Hum. Retroviruses, 20(3):315-325, Mar 2004. PubMed ID: 15117455. Show all entries for this paper.


Displaying record number 200517

Download this epitope record as JSON.

HXB2 Location Gag(167-176)
p24(35-44)
DNA(1288..1317)
Gag Epitope Map
Author Location p24(167-176 HXB2)
Epitope EVIPMFSALS Epitope Alignment
EVIPMFSALS epitope logo
Subtype B
Species (MHC/HLA) human(DRB1*01:01)
Immunogen HIV-1 infection
Patient MHC/HLA DQ1, DQ5, DR51, DRB1*01:01, DRB1*15:01
Experimental methods Intracellular cytokine staining, Proliferation, T-cell Elispot
Keywords HAART, ART

Notes

References

Boritz2003a Eli Boritz, Brent E. Palmer, Brian Livingston, Alessandro Sette, and Cara C. Wilson. Diverse Repertoire of HIV-1 p24-Specific, IFN-gamma-Producing CD4+ T Cell Clones Following Immune Reconstitution on Highly Active Antiretroviral Therapy. J. Immunol., 170(2):1106-1016, 15 Jan 2003. PubMed ID: 12517980. Show all entries for this paper.


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