HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 70

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HXB2 Location Pol(191-207)
RT(36-52)
DNA(2655..2705)
Pol Epitope Map
Author Location RT(36-52 BRU)
Epitope EICTEMEKEGKISKIGP Epitope Alignment
EICTEMEKEGKISKIGP epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

DeGroot1991 A. S. De Groot, M. Clerici, A. Hosmalin, S. H. Hughes, D. Barnd, C. W. Hendrix, R. Houghten, G. M. Shearer, and J. A. Berzofsky. Human Immunodeficiency Virus Reverse Transcriptase T-Helper Epitopes Identified in Mice and Humans: Correlation with a Cytotoxic T Cell Epitope. J. Infect. Dis., 164:1058-1065, 1991. This peptide stimulates both murine helper and cytotoxic T-cells and was able to stimulate IL-2 producing T-cells from 9 out of 17 HIV seropositive humans. RT epitope: CTEMEKEGKISKIGP. PubMed ID: 1720151. Show all entries for this paper.


Displaying record number 201385

Download this epitope record as JSON.

HXB2 Location Pol(191-207)
RT(36-52)
DNA(2655..2705)
Pol Epitope Map
Author Location RT(36-52)
Epitope EICTEMEKEGKISKIGP Epitope Alignment
EICTEMEKEGKISKIGP epitope logo
Species (MHC/HLA) human
Immunogen vaccine
Country Russia
Experimental methods T-cell Elispot
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, virus-like particle (VLP), HIV infected-cell lysate, polyepitope
Vaccine component Env, Gag, Nef, Pol

Notes

References

Bazhan2008 Sergei I. Bazhan, Larisa I. Karpenko, Leonid R. Lebedev, Roman V. Uzhachenko, Pavel A. Belavin, Alexey M. Eroshkin, and Alexander A. Ilyichev. A Synergistic Effect of a Combined Bivalent DNA-Protein Anti-HIV-1 Vaccine Containing Multiple T- and B-Cell Epitopes of HIV-1 Proteins. Mol. Immunol., 45(3):661-669, Feb 2008. PubMed ID: 17869341. Show all entries for this paper.


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