Search T Helper/CD4+ T-Cell Epitope Database

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Displaying record number 19

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HXB2 Location	Gag(208-217) p24(76-85) DNA(1411..1440)	Gag Epitope Map
Author Location	p24(208-217)
Epitope	EAAEWDRVHP	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

• One of four immunogenic Gag peptides used in study of the proliferative response to p24.
• T-cells from 11 of 24 HIV+ individuals responded to this epitope.
• Improved assay system (increase in culture time to 8 days and addition of IL-2 to cultures) gave increased detection of proliferative response.

References

Adams1997 S. L. Adams, R. A. Biti, and G. J. Stewart. T-cell response to HIV in natural infection: optimized culture conditions for detecting responses to Gag peptides. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol., 15:257-263, 1997. PubMed ID: 9292583. Show all entries for this paper.