HIV molecular immunology database


Search T Helper/CD4+ T-Cell Epitope Database

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Displaying record number 21

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HXB2 Location Gag(213-227)
Gag Epitope Map
Author Location p24(215-229 SF2)
Epitope DRVHPVHAGPIAPGQ Epitope Alignment
Species (MHC/HLA) macaque
Immunogen vaccine
Experimental methods  

Vaccine Details

Vaccine type virus-like particle (VLP)
Vaccine strain B clade SF2
Vaccine component p24 Gag



Mills1990 K. H. G. Mills, A. L. Barnard, B. P. Mahon, P. A. Kitchin, S. E. Adams, S. M. Kingsman, and A. J. Kingsman. Induction of HIV-Specific Immune Responses in Primates: Fine Specificity of Antibody and Helper T-Cell Recognition of the HIV p24 Protein. Vaccines, 90:213-218, 1990. Notes: Four cynomolgous macaques were immunized with 3 doses of p24 TY virus-like particles and their immune response was followed. Three 15 mer peptides stimulated CD4 T-cells proliferation and IL-2 production. Two of these responses were verified at the clonal level. B-cell responses were also studied in this paper. Show all entries for this paper.

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