HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 201135

Download this epitope record as JSON.

HXB2 Location Gag(480-494)
p2p7p1p6(117-131)
DNA(2227..2271)
Gag Epitope Map
Author Location p6(32-46 clade B consensus)
Epitope DKELYPLASLRSLFG Epitope Alignment
DKELYPLASLRSLFG epitope logo
Subtype B
Species (MHC/HLA) human(DRB1*01:01, DRB1*04:01, DRB1*04:05, DRB1*07:01, DRB1*11:01, DRB1*15:01, DRB5*01:01)
Immunogen HIV-1 infection
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, computational epitope prediction, HLA cross-presentation, chronic infection

Notes

References

Fonseca2006 Simone G Fonseca, Adriana Coutinho-Silva, Luiz Augusto M. Fonseca, Aluisio C. Segurado, Sandra L. Moraes, Hélcio Rodrigues, Juergen Hammer, Esper G. Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Identification of Novel Consensus CD4 T-Cell Epitopes from Clade B HIV-1 Whole Genome That Are Frequently Recognized by HIV-1 Infected Patients. AIDS, 20(18):2263-2273, 28 Nov 2006. PubMed ID: 17117012. Show all entries for this paper.


Displaying record number 201872

Download this epitope record as JSON.

HXB2 Location Gag(480-494)
p2p7p1p6(117-131)
DNA(2227..2271)
Gag Epitope Map
Author Location p6(32-46)
Epitope DKELYPLASLRSLFG Epitope Alignment
DKELYPLASLRSLFG epitope logo
Epitope Name p632-46
Subtype B
Species (MHC/HLA) mouse
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type DNA
Vaccine strain B clade
Adjuvant GM-CSF

Notes

References

Santana2015 Vinicius Canato Santana, Rafael Ribeiro Almeida, Susan Pereira Ribeiro, Luís Carlos de Souza Ferreira, Jorge Kalil, Daniela Santoro Rosa, and Edecio Cunha-Neto. Co-Administration of Plasmid-Encoded Granulocyte-Macrophage Colony-Stimulating Factor Increases Human Immunodeficiency Virus-1 DNA Vaccine-Induced Polyfunctional CD4+ T-Cell Responses. Mem. Inst. Oswaldo Cruz, 110(8):1010-1016, Dec 2015. PubMed ID: 26602876. Show all entries for this paper.


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