HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 1 matching record:

Displaying record number 74

Download this epitope record as JSON.

HXB2 Location Pol(217-232)
RT(62-77)
DNA(2733..2780)
Pol Epitope Map
Author Location RT(62-77 BRU)
Epitope AIKKKDSTKWRKLVDF Epitope Alignment
AIKKKDSTKWRKLVDF epitope logo
Species (MHC/HLA) mouse(H-2k)
Immunogen vaccine
Experimental methods  
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade BRU
Vaccine component RT

Notes

References

DeGroot1991 A. S. De Groot, M. Clerici, A. Hosmalin, S. H. Hughes, D. Barnd, C. W. Hendrix, R. Houghten, G. M. Shearer, and J. A. Berzofsky. Human Immunodeficiency Virus Reverse Transcriptase T-Helper Epitopes Identified in Mice and Humans: Correlation with a Cytotoxic T Cell Epitope. J. Infect. Dis., 164:1058-1065, 1991. This peptide stimulates both murine helper and cytotoxic T-cells and was able to stimulate IL-2 producing T-cells from 9 out of 17 HIV seropositive humans. RT epitope: CTEMEKEGKISKIGP. PubMed ID: 1720151. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health