HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 12 matching records:

Displaying record number 201427

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HXB2 Location Gag(139-153)
p24(7-21)
DNA(1204..1248)
Gag Epitope Map
Author Location Gag(171-)
Epitope QGQMVHQAISPRTLN Epitope Alignment
QGQMVHQAISPRTLN epitope logo
Epitope Name Gag171
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201428

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HXB2 Location Gag(259-273)
p24(127-141)
DNA(1564..1608)
Gag Epitope Map
Author Location Gag(294-)
Epitope GEIYKRWIILGLNKI Epitope Alignment
GEIYKRWIILGLNKI epitope logo
Epitope Name Gag294
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201429

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HXB2 Location Gag(263-277)
p24(131-145)
DNA(1576..1620)
Gag Epitope Map
Author Location Gag(298-)
Epitope KRWIILGLNKIVRMY Epitope Alignment
KRWIILGLNKIVRMY epitope logo
Epitope Name Gag298
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201430

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HXB2 Location Pol(279-293)
RT(124-138)
DNA(2919..2963)
Pol Epitope Map
Author Location Pol(303-)
Epitope FRKYTAFTIPSINNE Epitope Alignment
FRKYTAFTIPSINNE epitope logo
Epitope Name Pol303
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201431

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HXB2 Location Pol(311-325)
RT(156-170)
DNA(3015..3059)
Pol Epitope Map
Author Location Pol(335-)
Epitope SPAIFQSSMTKILEP Epitope Alignment
SPAIFQSSMTKILEP epitope logo
Epitope Name Pol335
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201436

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HXB2 Location Pol(592-606)
RT(437-451)
DNA(3858..3902)
Pol Epitope Map
Author Location Pol(619-)
Epitope AETFYVDGAANRETK Epitope Alignment
AETFYVDGAANRETK epitope logo
Epitope Name Pol619
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201432

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HXB2 Location Pol(684-698)
RT(529-543)
DNA(4134..4178)
Pol Epitope Map
Author Location Pol(711-)
Epitope EKVYLAWVPAHKGIG Epitope Alignment
EKVYLAWVPAHKGIG epitope logo
Epitope Name Pol711
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201433

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HXB2 Location Pol(685-699)
RT(530-544)
DNA(4137..4181)
Pol Epitope Map
Author Location Pol(712-)
Epitope KVYLAWVPAHKGIGG Epitope Alignment
KVYLAWVPAHKGIGG epitope logo
Epitope Name Pol712
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201434

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HXB2 Location Pol(888-902)
Integrase(173-187)
DNA(4746..4790)
Pol Epitope Map
Author Location Pol(915-)
Epitope KTAVQMAVFIHNFKR Epitope Alignment
KTAVQMAVFIHNFKR epitope logo
Epitope Name Pol915
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201435

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HXB2 Location Pol(929-943)
Integrase(214-228)
DNA(4869..4913)
Pol Epitope Map
Author Location Pol(956-)
Epitope QKQITKIQNFRVYYR Epitope Alignment
QKQITKIQNFRVYYR epitope logo
Epitope Name Pol956
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201437

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HXB2 Location Vpu(30-44)
DNA(6149..6193)
Vpu Epitope Map
Author Location Vpu(31-)
Epitope YRKILRQRKIDRLID Epitope Alignment
YRKILRQRKIDRLID epitope logo
Epitope Name Vpu31
Species (MHC/HLA) transgenic mouse(DR)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine component Env, Gag, Pol, Vpu

Notes

References

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


Displaying record number 201618

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HXB2 Location HIV-1 HIV-1 Epitope Map
Author Location  
Epitope
Subtype B, multiple
Species (MHC/HLA) human(DR1, DR4, DR7)
Immunogen vaccine
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type DNA prime with modified vaccinia Ankara (MVA) boost
Vaccine strain B clade, multiple epitope immunogen, other

Notes

References

Gorse2012 Geoffrey J. Gorse, Mark J. Newman, Allan deCamp, Christine Mhorag Hay, Stephen C. De Rosa, Elizabeth Noonan, Brian D. Livingston, Jonathan D. Fuchs, Spyros A. Kalams, Farah L. Cassis-Ghavami, and NIAID HIV Vaccine Trials Network. DNA and Modified Vaccinia Virus Ankara Vaccines Encoding Multiple Cytotoxic and Helper T-Lymphocyte Epitopes of Human Immunodeficiency Virus Type 1 (HIV-1) Are Safe but Weakly Immunogenic in HIV-1-Uninfected, Vaccinia Virus-Naive Adults. Clin. Vaccine Immunol., 19(5):649-658, May 2012. PubMed ID: 22398243. Show all entries for this paper.

Jin2009 Xia Jin, Mark J Newman, Stephen De-Rosa, Cristine Cooper, Evan Thomas, Michael Keefer, Jonathan Fuchs, William Blattner, Brian D. Livingston, Denise M. McKinney, Elizabeth Noonan, Allan deCamp, Olivier D. Defawe, Margaret Wecker, and NIAID HIV Vaccine Trials Network. A Novel HIV T Helper Epitope-Based Vaccine Elicits Cytokine-Secreting HIV-Specific CD4+ T Cells in a Phase I Clinical Trial in HIV-Uninfected Adults. Vaccine, 27(50):7080-7086, 23 Nov 2009. PubMed ID: 19786145. Show all entries for this paper.

Walker2009 Leslie E. Walker, Lo Vang, Xuefei Shen, Brian D. Livingston, Penny Post, Alessandro Sette, C. Steven Godin, and Mark J. Newman. Design and Preclinical Development of a Recombinant Protein and DNA Plasmid Mixed Format Vaccine to Deliver HIV-Derived T-Lymphocyte Epitopes. Vaccine, 27(50):7087-7095, 23 Nov 2009. PubMed ID: 19786132. Show all entries for this paper.


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