Found 9 matching records:
Download this epitope record as JSON.
HXB2 Location | Env(32-44) gp120(32-44) DNA(6318..6356) |
Env Epitope Map |
---|---|---|
Author Location | gp120(39-51) | |
Epitope |
EQLWVTVYYGVPV
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2bxk) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(38-48) gp120(38-48) DNA(6336..6368) |
Env Epitope Map |
---|---|---|
Author Location | gp120(45-55) | |
Epitope |
VYYGVPVWKEA
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2bxk, H-2sxd) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(41-54) gp120(41-54) DNA(6345..6386) |
Env Epitope Map |
---|---|---|
Author Location | gp120(48-61) | |
Epitope |
GVPVWKEATTLFC
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2sxd) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(65-75) gp120(65-75) DNA(6417..6449) |
Env Epitope Map |
---|---|---|
Author Location | gp120(72-82) | |
Epitope |
AHKVWATHACV
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2bxk, H-2sxd) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(74-85) gp120(74-85) DNA(6444..6479) |
Env Epitope Map |
---|---|---|
Author Location | gp120(81-92) | |
Epitope |
CVPTNPVPQEVV
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2bxk, H-2sxd) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(102-114) gp120(102-114) DNA(6528..6566) |
Env Epitope Map |
---|---|---|
Author Location | gp120(109-121) | |
Epitope |
EQMHEDIISLWDQ
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2bxk) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(199-211) gp120(199-211) DNA(6819..6857) |
Env Epitope Map |
---|---|---|
Author Location | gp120(204-216) | |
Epitope |
SVITQACSKVSFE
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2bxk, H-2sxd) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(210-223) gp120(210-223) DNA(6852..6893) |
Env Epitope Map |
---|---|---|
Author Location | gp120(215-228) | |
Epitope |
FEPIPIHYCAFPGF
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(H-2bxk) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Env(519-543) gp41(8-32) DNA(7779..7853) |
Env Epitope Map |
---|---|---|
Author Location | gp41(519-543) | |
Epitope |
FLGFLGAAGSTMGAASLTLTVQARC
|
Epitope Alignment |
Species (MHC/HLA) | mouse(H-2bxk, H-2sxd) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords |
Vaccine type | peptide |
---|
Sastry1991 K. J. Sastry and R. B. Arlinghaus. Identification of T-Cell Epitopes without B-Cell Activity in the First and Second Conserved Regions of the HIV Env Protein. AIDS, 5:699-707, 1991. Notes: Seven out of 19 peptides induced good T-cell proliferative response in mice representing four major histocompatibility complex haplotypes, without eliciting an Ab response. Eleven peptides were able to induce T-cells that could proliferate in response to recombinant gp160 (greater than or equal to 3 fold relative to unrelated peptides). Peptides were modified to generate polymers with disulfide bonds or micelles with palmitic acid residues attached to the amino-terminal lysine; in these configurations peptides were immunogenic without being coupled to a carrier molecule. F1 hybrid mice were used: ASW x BALBc F1 (H-2$^kxb$) and B6C3 F1 (H-2$^sxd$). PubMed ID: 1715718. Show all entries for this paper.
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