HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 16 matching records:

Displaying record number 201623

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HXB2 Location Pol(109-131)
Protease(53-75)
DNA(2409..2477)
Pol Epitope Map
Author Location Protease(53-75 M)
Epitope FIKVRQYDQILIEICGKKAIGTV Epitope Alignment
Epitope Name Protease(53-75)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*02:01, DPB1*01:01; DQA1*01:02, DQB1*05:02; DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*03:01; DPA1*01:03, DPB1*04:01; DPA1*03:01, DPB1*04:02; DPB1*02:01, DPB1*05:01; DPA1*01:03, DPB1*20:01; DQA1*03:01, DQB1*03:01; DQA1*01:01, DQB1*05:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201627

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HXB2 Location Pol(135-151)
Protease(79-95)
DNA(2487..2537)
Pol Epitope Map
Author Location Protease(79-95 M)
Epitope PTPVNIIGRNMLTQIGC Epitope Alignment
PTPVNIIGRNMLTQIGC epitope logo
Epitope Name Protease(79-95)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*03:01; DPA1*01:03, DPB1*04:01; DPA1*03:01, DPB1*04:02
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201628

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HXB2 Location Pol(498-512)
RT(343-357)
DNA(3576..3620)
Pol Epitope Map
Author Location RT(343-357 M)
Epitope QEPFKNLKTGKYAKM Epitope Alignment
QEPFKNLKTGKYAKM epitope logo
Epitope Name RT(343-357)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*02:01, DPB1*01:01; DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*04:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201629

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HXB2 Location Pol(509-523)
RT(354-368)
DNA(3609..3653)
Pol Epitope Map
Author Location Protease(354-368 M)
Epitope YAKMRSAHTNDVKQL Epitope Alignment
YAKMRSAHTNDVKQL epitope logo
Epitope Name Protease(354-368)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*02:01; DPA1*02:01, DPB1*14:01; DPA1*01:03, DPB1*20:01; DQA1*03:01, DQB1*03:01; DQA1*01:02, DQB1*06:02; DQA1*01:03, DQB1*06:03
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201630

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HXB2 Location Pol(524-546)
RT(369-391)
DNA(3654..3722)
Pol Epitope Map
Author Location Protease(369-391 M)
Epitope TEAVQKIATESIVIWGKTPKFRL Epitope Alignment
Epitope Name RT(369-391)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPB1*02:01, DPB1*05:01; DPA1*02:01, DPB1*14:01; DPA1*01:03, DPB1*20:01; DQA1*02:01, DQB1*02:02; DQA1*01:03, DQB1*06:03; DQA1*01:01, DQB1*05:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201631

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HXB2 Location Pol(568-582)
RT(413-427)
DNA(3786..3830)
Pol Epitope Map
Author Location Protease(413-427 M)
Epitope EWEFVNTPPLVKLWY Epitope Alignment
EWEFVNTPPLVKLWY epitope logo
Epitope Name Protease(413-427)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*02:01, DPB1*01:01; DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*04:01; DPA1*01:03, DPB1*20:01; DQA1*05:01, DQB1*02:01; DQA1*01:01, DQB1*05:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201632

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HXB2 Location Pol(586-600)
RT(431-445)
DNA(3840..3884)
Pol Epitope Map
Author Location Protease(431-445 M)
Epitope KEPIVGAETFYVDGA Epitope Alignment
KEPIVGAETFYVDGA epitope logo
Epitope Name Protease(431-445)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*02:01, DPB1*01:01; DQA1*01:04, DQB1*05:03; DQA1*01:02, DQB1*06:02; DQA1*01:03, DQB1*06:03; DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*04:01; DPA1*03:01, DPB1*04:02; DQA1*05:01, DQB1*02:01; DQA1*02:01, DQB1*02:02; DQA1*03:01, DQB1*03:01; DQA1*05:01, DQB1*03:01; DQA1*04:01, DQB1*04:02
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201654

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HXB2 Location Pol(683-701)
RT(528-546)
DNA(4131..4187)
Pol Epitope Map
Author Location RT(528-546 M)
Epitope KEKVYLSWVPAHKGIGGNE Epitope Alignment
KEKVYLSWVPAHKGIGGNE epitope logo
Epitope Name RT(528-546)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*02:01, DPB1*01:01; DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*03:01; DPA1*03:01, DPB1*04:02; DPA1*01:03, DPB1*20:01; DQA1*03:01, DQB1*03:01; DQA1*05:01, DQB1*03:01; DQA1*01:02, DQB1*06:02; DQA1*01:03, DQB1*06:03
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201655

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HXB2 Location Pol(743-758)
Integrase(28-43)
DNA(4311..4358)
Pol Epitope Map
Author Location Integrase(28-43 M)
Epitope LPPIVAKEIVASCDKC Epitope Alignment
LPPIVAKEIVASCDKC epitope logo
Epitope Name Integrase(28-43)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*02:01; DPA1*03:01, DPB1*04:02; DPA1*01:03, DPB1*20:01; DQA1*03:01, DQB1*03:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201656

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HXB2 Location Pol(784-800)
Integrase(69-85)
DNA(4434..4484)
Pol Epitope Map
Author Location Integrase(69-85 M)
Epitope EGKIILVAVHVASGYIE Epitope Alignment
EGKIILVAVHVASGYIE epitope logo
Epitope Name Integrase(69-85)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*02:01; DPA1*03:01, DPB1*04:02; DPA1*01:03, DPB1*20:01; DQA1*03:01, DQB1*03:01; DQA1*01:01, DQB1*05:01; DQA1*01:02, DQB1*05:02; DQA1*01:04, DQB1*05:03; DQA1*01:02, DQB1*06:02
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201657

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HXB2 Location Pol(811-828)
Integrase(96-113)
DNA(4515..4568)
Pol Epitope Map
Author Location Integrase(96-113 M)
Epitope ETAYFILKLAGRWPVKVI Epitope Alignment
ETAYFILKLAGRWPVKVI epitope logo
Epitope Name Integrase(96-113)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*02:01, DPB1*01:01; DQA1*01:02, DQB1*06:02; DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*04:01; DPA1*03:01, DPB1*04:02; DPB1*02:01, DPB1*05:01; DPA1*01:03, DPB1*20:01; DQA1*01:01, DQB1*05:01; DQA1*01:02, DQB1*05:02; DQA1*01:04, DQB1*05:03
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201706

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HXB2 Location Pol(931-950)
Integrase(216-235)
DNA(4875..4934)
Pol Epitope Map
Author Location Integrase(216-235 M)
Epitope QITKIQNFRVYYRDSRDPIW Epitope Alignment
QITKIQNFRVYYRDSRDPIW epitope logo
Epitope Name Integrase(216-235)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*03:01; DPB1*02:01, DPB1*05:01; DQA1*01:03, DQB1*06:03
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201704

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HXB2 Location Pol(964-983)
Integrase(249-268)
DNA(4974..5033)
Pol Epitope Map
Author Location Integrase(249-268 M)
Epitope VVIQDNSDIKVVPRRKAKII Epitope Alignment
VVIQDNSDIKVVPRRKAKII epitope logo
Epitope Name Integrase(249-268)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*03:01; DPB1*02:01, DPB1*05:01; DQA1*01:03, DQB1*06:03
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201705

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HXB2 Location Vpu(13-26)
DNA(6098..6139)
Vpu Epitope Map
Author Location Vpu(53-75 M)
Epitope IVALIIAIVVWTIV Epitope Alignment
IVALIIAIVVWTIV epitope logo
Epitope Name Vpu(13-26)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201658

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HXB2 Location Nef(67-87)
DNA(8995..9057)
Nef Epitope Map
Author Location Nef(67-87 M)
Epitope GFPVRPQVPLRPMTYKGAFDL Epitope Alignment
Epitope Name Nef(67-87)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*03:01; DPA1*03:01, DPB1*04:02; DQA1*03:01, DQB1*03:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


Displaying record number 201703

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HXB2 Location Nef(133-156)
DNA(9193..9264)
Nef Epitope Map
Author Location Nef(133-156 M)
Epitope IRYPLTFGWCFKLVPVDPREVEEA Epitope Alignment
Epitope Name Nef(133-156)
Subtype A1, B, C, D, F1, F2, G, H
Species (MHC/HLA) human, humanized mouse, mouse
Immunogen vaccine
Patient MHC/HLA DPA1*01:03, DPB1*02:01; DPA1*01:03, DPB1*04:01; DPA1*03:01, DPB1*04:02; DQA1*03:01, DQB1*03:01; DQA1*01:01, DQB1*05:01
Country Brazil
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Proliferation
Keywords subtype comparisons, computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine component Gag, Nef, Pol, Rev, Vif, Vpr, Vpu

Notes

References

Almeida2012 Rafael Ribeiro Almeida, Daniela Santoro Rosa, Susan Pereira Ribeiro, Vinicius Canato Santana, Esper Georges Kallás, John Sidney, Alessandro Sette, Jorge Kalil, and Edecio Cunha-Neto. Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides. PLoS One, 7(9):e45267, 2012. PubMed ID: 23028895. Show all entries for this paper.


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