Found 5 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(277-285) p24(145-153) DNA(1618..1644) |
Gag Epitope Map |
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Author Location | Gag | |
Epitope |
YSPTSILDI
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(C*01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | LTNP/EC-16: A*01, A*33, B*08, B*53, C*01, C*04 | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, immunodominance |
Migueles2015 Stephen A. Migueles, Daniel Mendoza, Matthew G. Zimmerman, Kelly M. Martins, Sushila A. Toulmin, Elizabeth P. Kelly, Bennett A. Peterson, Sarah A. Johnson, Eric Galson, Kate O. Poropatich, Andy Patamawenu, Hiromi Imamichi, Alexander Ober, Catherine A. Rehm, Sara Jones, Claire W. Hallahan, Dean A. Follmann, and Mark Connors. CD8+ T-Cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen Types. EBioMedicine, 2(1):46-58, Jan 2015. PubMed ID: 26137533. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(277-285) p24(145-153) DNA(1618..1644) |
Gag Epitope Map |
---|---|---|
Author Location | p24(145-153) | |
Epitope |
YSPTSILDI
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | Gag YI9 | |
Subtype | B | |
Species (MHC/HLA) | human(C*01:02) | |
Immunogen | HIV-1 infection | |
Country | Japan | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | subtype comparisons, variant cross-reactivity, optimal epitope, novel epitope, chronic infection |
Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(277-285) p24(145-153) DNA(1618..1644) |
Gag Epitope Map |
---|---|---|
Author Location | ||
Epitope |
YSPTSILDI
|
Epitope Alignment
|
Epitope Name | YI9 | |
Subtype | B | |
Species (MHC/HLA) | human(C*01:02) | |
Immunogen | HIV-1 infection, vaccine | |
Country | Japan | |
Experimental methods | CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining | |
Keywords | vaccine-induced immune responses, variant cross-reactivity |
Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(277-285) p24(145-153) DNA(1618..1644) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(277-285) | |
Epitope |
YSPTSILDI
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | YI9-4T GagYI9-4T, YI9, Gag-YI9 | |
Subtype | B | |
Species (MHC/HLA) | human(C*01:02) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | VI-087: A*02:01, C*01:02; VI-047: C*01:02; VI-090: C*01:02; VI-165: C*01:02; VI-230: C*01:02; VI-346: C*01:02 | |
Country | Japan, Viet Nam | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA stabilization assay, Intracellular cytokine staining, Other, Relative replication capacity assay, Tetramer binding | |
Keywords | subtype comparisons, escape, variant cross-reactivity, mutation acquisition, viral fitness and/or reversion, HLA associated polymorphism, chronic infection |
Zhang2021 Yu Zhang, Hayato Murakoshi, Takayuki Chikata, Tomohiro Akahoshi, Giang Van Tran, Trung Vu Nguyen, Hiroyuki Gatanaga, Kinh Van Nguyen, Shinichi Oka, Nozomi Kuse, and Masafumi Takiguchi. Effect of Difference in Consensus Sequence between HIV-1 Subtype A/E and Subtype B Viruses on Elicitation of Gag-Specific CD8+ T Cells and Accumulation of HLA-Associated Escape Mutations. J. Virol., 95(6), 24 Feb 2021. PubMed ID: 33361435. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(277-285) p24(145-153) DNA(1618..1644) |
Gag Epitope Map |
---|---|---|
Author Location | Gag | |
Epitope |
YSPTSILDI
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human(C*12) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | escape, HLA associated polymorphism |
Blais2012 Marie-Eve Blais, Yonghong Zhang, Tim Rostron, Harry Griffin, Stephen Taylor, Keyi Xu, Huiping Yan, Hao Wu, Ian James, Mina John, Tao Dong, and Sarah L. Rowland-Jones. High Frequency of HIV Mutations Associated with HLA-C Suggests Enhanced HLA-C-Restricted CTL Selective Pressure Associated with an AIDS-Protective Polymorphism. J. Immunol., 188(9):4663-4670, 1 May 2012. PubMed ID: 22474021. Show all entries for this paper.
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