Found 19 matching records:
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(357-365) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL9 | |
Species (MHC/HLA) | human(A*34) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | B40-IL9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*40) | |
Immunogen | HIV-1 infection | |
Country | Canada | |
Experimental methods | Chromium-release assay, Other | |
Keywords | epitope processing, escape |
Zhang2012 Shao Chong Zhang, Eric Martin, Mariko Shimada, Sasha Blue Godfrey, Jennifer Fricke, Shirley Locastro, Nicole Y. Lai, Paul Liebesny, Jonathan M. Carlson, Chanson J. Brumme, Oluwatobi Awele Ogbechie, Huabiao Chen, Bruce D. Walker, Zabrina L. Brumme, Daniel G. Kavanagh, and Sylvie Le Gall. Aminopeptidase Substrate Preference Affects HIV Epitope Presentation and Predicts Immune Escape Patterns in HIV-Infected Individuals. J. Immunol., 188(12):5924-5934, 15 Jun 2012. PubMed ID: 22586036. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(357-365) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL9 | |
Species (MHC/HLA) | human(B*40) | |
Immunogen | in vitro stimulation or selection | |
Experimental methods | Chromium-release assay | |
Keywords | assay or method development, variant cross-reactivity, characterizing CD8+ T cells |
Balamurugan2018 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Cross-Reactivity against Multiple HIV-1 Epitopes Is Characteristic of HIV-1-Specific Cytotoxic T Lymphocyte Clones. J. Virol., 92(16), 15 Aug 2018. PubMed ID: 29899094. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | ||
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B40) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | supertype, HLA cross-presentation |
Frahm2007b Nicole Frahm, Karina Yusim, Todd J. Suscovich, Sharon Adams, John Sidney, Peter Hraber, Hannah S. Hewitt, Caitlyn H. Linde, Daniel G. Kavanagh, Tonia Woodberry, Leah M. Henry, Kellie Faircloth, Jennifer Listgarten, Carl Kadie, Nebojsa Jojic, Kaori Sango, Nancy V. Brown, Eunice Pae, M. Tauheed Zaman, Florian Bihl, Ashok Khatri, Mina John, Simon Mallal, Francesco M. Marincola, Bruce D . Walker, Alessandro Sette, David Heckerman, Bette T. Korber, and Christian Brander. Extensive HLA Class I Allele Promiscuity among Viral CTL Epitopes. Eur. J. Immunol., 37(9):2419-2433, Sep 2007. PubMed ID: 17705138. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL-9 | |
Species (MHC/HLA) | human(B40) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | escape, TCR usage, mutation acquisition |
Yu2007 Xu G. Yu, Mathias Lichterfeld, Katie L. Williams, Javier Martinez-Picado, and Bruce D. Walker. Random T-Cell Receptor Recruitment in Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T Cells from Genetically Identical Twins Infected with the Same HIV-1 Strain. J Virol, 81(22):12666-12669, Nov 2007. PubMed ID: 17804503. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL9(RT) | |
Subtype | B | |
Species (MHC/HLA) | human(B40) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | B40-IL9(RT) | |
Species (MHC/HLA) | human(B40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT(202-210 LAI) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*40:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Altfeld2000 M. A. Altfeld, A. Trocha, R. L. Eldridge, E. S. Rosenberg, M. N. Phillips, M. M. Addo, R. P. Sekaly, S. A. Kalams, S. A. Burchett, K. McIntosh, B. D. Walker, and P. J. Goulder. Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay. J. Virol., 74:8541, 2000. PubMed ID: 10954555. Show all entries for this paper.
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(357-365) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | IL9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*40:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*02:01, A*24:02, B*40:01, B*50:01, C*03, Cw4; TW1: A*02:01, A*24:02, B*40:01, B*50:01, C*03, C*04; TW2: A*02:01, A*24:02, B*40:01, B*50:01, C*03, C*04 | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | immunodominance, escape, variant cross-reactivity |
Draenert2006 Rika Draenert, Todd M. Allen, Yang Liu, Terri Wrin, Colombe Chappey, Cori L. Verrill, Guillem Sirera, Robert L. Eldridge, Matthew P. Lahaie, Lidia Ruiz, Bonaventura Clotet, Christos J. Petropoulos, Bruce D. Walker, and Javier Martinez-Picado. Constraints on HIV-1 Evolution and Immunodominance Revealed in Monozygotic Adult Twins Infected with the Same Virus. J. Exp. Med., 203(3):529-539, 20 Mar 2006. PubMed ID: 16533886. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Subtype | A, CRF02_AG, CRF06_cpx, CRF09_cpx | |
Species (MHC/HLA) | human(B*60) | |
Immunogen | HIV-1 infection | |
Country | Burkina Faso | |
Experimental methods | Other | |
Keywords | drug resistance |
Tebit2009 Denis M. Tebit, Lassana Sangaré, Fabrice Tiba, Yameogo Saydou, Aline Makamtse, Hermann Somlare, Guillaume Bado, Boris G. Kouldiaty, Inoussa Zabsonre, Sibiri L. Yameogo, Kanokporn Sathiandee, Joseph Y. Drabo, and Hans-Georg Kräusslich. Analysis of the Diversity of the HIV-1 pol Gene and Drug Resistance Associated Changes among Drug-Naïve Patients in Burkina Faso. J. Med. Virol., 81(10):1691-701, Oct 2009. PubMed ID: 19697403. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT(202-210) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*60, B*61) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords |
Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT( SF2) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B60) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | AC21: A24, A3, B18, B60, Cw10, Cw7 | |
Experimental methods | ||
Keywords | HAART, ART, acute/early infection |
Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL9 | |
Species (MHC/HLA) | human(B60) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A2, A24, B38, B60, C*12, Cw2 | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HAART, ART, supervised treatment interruptions (STI), early treatment |
Montefiori2003 David C. Montefiori, Marcus Altfeld, Paul K. Lee, Miroslawa Bilska, Jintao Zhou, Mary N. Johnston, Feng Gao, Bruce D. Walker, and Eric S. Rosenberg. Viremia Control Despite Escape from a Rapid and Potent Autologous Neutralizing Antibody Response after Therapy Cessation in an HIV-1-Infected Individual. J. Immunol., 170(7):3906-3914, Apr 2003. PubMed ID: 12646660. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT( SF2) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B60) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords |
Altfeld2000 M. A. Altfeld, A. Trocha, R. L. Eldridge, E. S. Rosenberg, M. N. Phillips, M. M. Addo, R. P. Sekaly, S. A. Kalams, S. A. Burchett, K. McIntosh, B. D. Walker, and P. J. Goulder. Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay. J. Virol., 74:8541, 2000. PubMed ID: 10954555. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(357-365) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL9 | |
Species (MHC/HLA) | human(C*03) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | B40-IL9 | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | immunodominance, acute/early infection, chronic infection |
Streeck2009a Hendrik Streeck, Jonathan S. Jolin, Ying Qi, Bader Yassine-Diab, Randall C. Johnson, Douglas S. Kwon, Marylyn M. Addo, Chanson Brumme, Jean-Pierre Routy, Susan Little, Heiko K. Jessen, Anthony D. Kelleher, Frederick M. Hecht, Rafick-Pierre Sekaly, Eric S. Rosenberg, Bruce D. Walker, Mary Carrington, and Marcus Altfeld. Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells. J. Virol., 83(15):7641-7648, Aug 2009. PubMed ID: 19458000. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | vaccine | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | vaccine-induced immune responses |
Vaccine type | adenovirus type 5 (Ad5), DNA prime with Ad5 boost |
---|---|
Vaccine strain | B clade IIIB, B clade JRFL, B clade CAM-1 |
Vaccine component | Gag, Nef, Pol |
Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT(357-365 NL4-3) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL9 | |
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | epitope processing |
Rucevic2016 Marijana Rucevic, Georgio Kourjian, Julie Boucau, Renata Blatnik, Wilfredo Garcia Bertran, Matthew J. Berberich, Bruce D. Walker, Angelika B. Riemer, and Sylvie Le Gall. Analysis of Major Histocompatibility Complex-Bound HIV Peptides Identified from Various Cell Types Reveals Common Nested Peptides and Novel T Cell Responses. J. Virol., 90(19):8605-8620, 1 Oct 2016. PubMed ID: 27440904. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(357-365) RT(202-210) DNA(3153..3179) |
Pol Epitope Map |
---|---|---|
Author Location | RT(202-210) | |
Epitope |
IEELRQHLL
|
Epitope Alignment
|
Epitope Name | IL-9 | |
Subtype | B, C | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection, engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | acute/early infection, HLA associated polymorphism, chronic infection, protective allele |
Ojwach2018 Doty B. A. Ojwach, Daniel MacMillan, Tarylee Reddy, Vladimir Novitsky, Zabrina L. Brumme, Mark A. Brockman, Thumbi Ndung'u, and Jaclyn K. Mann. Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection. J. Virol., 92(19), 1 Oct 2018. PubMed ID: 29997209. Show all entries for this paper.
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