Search CTL/CD8+ T-Cell Epitope Database

Found 1 matching record:

Displaying record number 640

Download this epitope record as JSON.

HXB2 Location	gp160(42-52) gp120(42-52) DNA(6348..6380)	gp160 Epitope Map
Author Location	gp120(42-52 PV22)
Epitope	VPVWKEATTTL	Epitope Alignment
		Show epitope variants
Species (MHC/HLA)	human(B35)
Immunogen	HIV-1 infection
Experimental methods
Keywords	subtype comparisons

Notes

• VPVWKEATTTL is the consensus sequence for clades B and D.
• VPVWKdAeTTL is the consensus sequence for clade A and it is cross-reactive.
• VPVWKEAdTTL is the consensus sequence for clade C and it is cross-reactive.
• VPVWrdAdTTL is the consensus sequence for clade E and even with three substitutions still retains some cross-reactivity.

References

Cao1997a H. Cao, P. Kanki, J. L. Sankale, A. Dieng-Sarr, Gail P. Mazzara, S. Kalams, B. Korber, S. M'Boup, and B. D. Walker. CTL Cross-Reactivity among Different HIV-1 Clades: Implications for Vaccine Development. J. Virol., 71:8615-8623, 1997. PubMed ID: 9343219. Show all entries for this paper.