HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 10 matching records:

Displaying record number 55270

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location p24(164-172)
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords assay or method development, optimal epitope

Notes

References

Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.


Displaying record number 52525

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location p24(164-172)
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Species (MHC/HLA) human(A*02:07)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61783

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location  
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Epitope Name YL9
Subtype B
Species (MHC/HLA) human(A*02:07)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining
Keywords vaccine-induced immune responses, variant cross-reactivity

Notes

References

Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.


Displaying record number 52330

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location Gag(296-304)
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A*02:07)
Immunogen HIV-1 infection
Patient MHC/HLA A*02:07
Experimental methods  
Keywords subtype comparisons

Notes

References

Currier2002b Jeffrey R Currier, Mark deSouza, Penprapa Chanbancherd, Wendy Bernstein, Deborah L Birx, and Josephine H Cox. Comprehensive Screening for Human Immunodeficiency Virus Type 1 Subtype-Specific CD8 Cytotoxic T Lymphocytes and Definition of Degenerate Epitopes Restricted by HLA-A0207 and -Cw0304 Alleles. J. Virol., 76(10):4971-4986, May 2002. PubMed ID: 11967314. Show all entries for this paper.


Displaying record number 54229

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location p24
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Epitope Name A2-YL9(p24)
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 1464

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location p24(164-172)
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Species (MHC/HLA) human(B70)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 61784

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location  
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Epitope Name YL9
Subtype B
Species (MHC/HLA) human(C*03)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining
Keywords vaccine-induced immune responses, variant cross-reactivity

Notes

References

Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.


Displaying record number 61506

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location Gag(296-304)
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Epitope Name GagYL9
Subtype B
Species (MHC/HLA) human(C*03:04)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords optimal epitope, chronic infection

Notes

References

Murakoshi2015 Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Naoki Ishizuka, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes. J. Virol., 89(10):5330-5339, May 2015. PubMed ID: 25741000. Show all entries for this paper.


Displaying record number 62818

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location p24(296-304)
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


Displaying record number 55899

Download this epitope record as JSON.

HXB2 Location Gag(296-304)
p24(164-172)
DNA(1675..1701)
Gag Epitope Map
Author Location p24
Epitope YVDRFYKTL Epitope Alignment
YVDRFYKTL epitope logo
Show epitope variants
Epitope Name YL9(p24)
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity, chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health