HIV molecular immunology database
Found 10 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | p24(164-172) | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*02) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other | |
Keywords | assay or method development, optimal epitope |
Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | p24(164-172) | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*02:07) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | ||
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Epitope Name | YL9 | |
Subtype | B | |
Species (MHC/HLA) | human(A*02:07) | |
Immunogen | HIV-1 infection, vaccine | |
Country | Japan | |
Experimental methods | CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining | |
Keywords | vaccine-induced immune responses, variant cross-reactivity |
Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(296-304) | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human(A*02:07) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*02:07 | |
Experimental methods | ||
Keywords | subtype comparisons |
Currier2002b Jeffrey R Currier, Mark deSouza, Penprapa Chanbancherd, Wendy Bernstein, Deborah L Birx, and Josephine H Cox. Comprehensive Screening for Human Immunodeficiency Virus Type 1 Subtype-Specific CD8 Cytotoxic T Lymphocytes and Definition of Degenerate Epitopes Restricted by HLA-A0207 and -Cw0304 Alleles. J. Virol., 76(10):4971-4986, May 2002. PubMed ID: 11967314. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | p24 | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Epitope Name | A2-YL9(p24) | |
Species (MHC/HLA) | human(A2) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | p24(164-172) | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B70) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords |
Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | ||
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Epitope Name | YL9 | |
Subtype | B | |
Species (MHC/HLA) | human(C*03) | |
Immunogen | HIV-1 infection, vaccine | |
Country | Japan | |
Experimental methods | CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining | |
Keywords | vaccine-induced immune responses, variant cross-reactivity |
Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(296-304) | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Epitope Name | GagYL9 | |
Subtype | B | |
Species (MHC/HLA) | human(C*03:04) | |
Immunogen | HIV-1 infection | |
Country | Japan | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other | |
Keywords | optimal epitope, chronic infection |
Murakoshi2015 Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Naoki Ishizuka, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes. J. Virol., 89(10):5330-5339, May 2015. PubMed ID: 25741000. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | p24(296-304) | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(296-304) p24(164-172) DNA(1675..1701) |
Gag Epitope Map |
---|---|---|
Author Location | p24 | |
Epitope |
YVDRFYKTL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | YL9(p24) | |
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | variant cross-reactivity, chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.