HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 57691

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location p24(277-285)
Epitope YSPVSILDI Epitope Alignment
YSPVSILDI epitope logo
Show epitope variants
Epitope Name YI9
Subtype CRF01_AE
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Country Thailand
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords immunodominance, escape, optimal epitope

Notes

References

Buranapraditkun2011 Supranee Buranapraditkun, Ursula Hempel, Patrawadee Pitakpolrat, Rachel L. Allgaier, Pattarawat Thantivorasit, Sven-Iver Lorenzen, Sunee Sirivichayakul, William H. Hildebrand, Marcus Altfeld, Christian Brander, Bruce D. Walker, Praphan Phanuphak, Pokrath Hansasuta, Sarah L. Rowland-Jones, Todd M. Allen, and Kiat Ruxrungtham. A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 clade CRF01\_AE Infected Thais. PLoS One, 6(8):e23603, 2011. PubMed ID: 21887282. Show all entries for this paper.


Displaying record number 58624

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location p24(277-285)
Epitope YSPVSILDI Epitope Alignment
YSPVSILDI epitope logo
Epitope Name YI9
Subtype CRF01_AE
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Country Thailand
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61028

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location p24(145-153)
Epitope YSPVSILDI Epitope Alignment
YSPVSILDI epitope logo
Subtype B
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Patient MHC/HLA 10849: A*2301, A*6801, B*3543, B*5703, Cw*0102, Cw*0210
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 61469

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location Gag(277-285)
Epitope YSPVSILDI Epitope Alignment
YSPVSILDI epitope logo
Show epitope variants
Epitope Name YI9
Subtype CRF01_AE
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Country Viet Nam
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords HLA associated polymorphism

Notes

References

VanTran2016 Giang Van Tran, Takayuki Chikata, Jonathan M. Carlson, Hayato Murakoshi, Dung Hoai Nguyen, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Sachiko Sakai, Kyle Cobarrubias, Shinichi Oka, Zabrina L. Brumme, Kinh Van Nguyen, Masafumi Takiguchi, and NHTD Treatment-Naive Cohort Study Group. A Strong Association of Human Leukocyte Antigen-Associated Pol and Gag Mutations with Clinical Parameters in HIV-1 Subtype A/E Infection. AIDS, 30(5):681-689, 13 Mar 2016. PubMed ID: 26595539. Show all entries for this paper.


Displaying record number 61541

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location p24(145-153)
Epitope YSPVSILDI Epitope Alignment
YSPVSILDI epitope logo
Show epitope variants
Epitope Name Gag YI9-4V
Subtype CRF01_AE
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Patient MHC/HLA KI-724: B*5201, Cw*0102
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, variant cross-reactivity, optimal epitope, novel epitope, chronic infection

Notes

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Displaying record number 57656

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location  
Epitope YSPVSILDI Epitope Alignment
YSPVSILDI epitope logo
Species (MHC/HLA) macaque
Immunogen vaccine
Experimental methods CD8 T-cell RecycleSpot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type DNA, modified vaccinia Ankara (MVA), Semliki-Forest Virus, adenovirus, Long Peptides, HIVconsv
Adjuvant Montanide (ISA 51)

Notes

References

Rosario2010 Maximillian Rosario, Anne Bridgeman, Esther D. Quakkelaar, Maire F. Quigley, Brenna J. Hill, Maria L. Knudsen, Virginia Ammendola, Karl Ljungberg, Nicola Borthwick, Eung-Jun Im, Andrew J. McMichael, Jan W. Drijfhout, Hui Yee Greenaway, Vanessa Venturi, Daniel C. Douek, Stefano Colloca, Peter Liljeström, Alfredo Nicosia, David A. Price, Cornelis J. M. Melief, and Tomáš Hanke. Long Peptides Induce Polyfunctional T Cells against Conserved Regions of HIV-1 with Superior Breadth to Single-Gene Vaccines in Macaques. Eur. J. Immunol., 40(7):1973-1984, Jul 2010. PubMed ID: 20468055. Show all entries for this paper.


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