HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 59411

Download this epitope record as JSON.

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location Gag
Epitope YSPTSILDI Epitope Alignment
YSPTSILDI epitope logo
Subtype B
Species (MHC/HLA) human(C*01)
Immunogen HIV-1 infection
Patient MHC/HLA LTNP/EC-16: A*01, A*33, B*08, B*53, C*01, C*04
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, immunodominance

Notes

References

Migueles2015 Stephen A. Migueles, Daniel Mendoza, Matthew G. Zimmerman, Kelly M. Martins, Sushila A. Toulmin, Elizabeth P. Kelly, Bennett A. Peterson, Sarah A. Johnson, Eric Galson, Kate O. Poropatich, Andy Patamawenu, Hiromi Imamichi, Alexander Ober, Catherine A. Rehm, Sara Jones, Claire W. Hallahan, Dean A. Follmann, and Mark Connors. CD8+ T-Cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen Types. EBioMedicine, 2(1):46-58, Jan 2015. PubMed ID: 26137533. Show all entries for this paper.


Displaying record number 61540

Download this epitope record as JSON.

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location p24(145-153)
Epitope YSPTSILDI Epitope Alignment
YSPTSILDI epitope logo
Show epitope variants
Epitope Name Gag YI9
Subtype B
Species (MHC/HLA) human(C*01:02)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, variant cross-reactivity, optimal epitope, novel epitope, chronic infection

Notes

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Displaying record number 61779

Download this epitope record as JSON.

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location  
Epitope YSPTSILDI Epitope Alignment
YSPTSILDI epitope logo
Epitope Name YI9
Subtype B
Species (MHC/HLA) human(C*01:02)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining
Keywords vaccine-induced immune responses, variant cross-reactivity

Notes

References

Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.


Displaying record number 58696

Download this epitope record as JSON.

HXB2 Location Gag(277-285)
p24(145-153)
DNA(1618..1644)
Gag Epitope Map
Author Location Gag
Epitope YSPTSILDI Epitope Alignment
YSPTSILDI epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(C*12)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, HLA associated polymorphism

Notes

References

Blais2012 Marie-Eve Blais, Yonghong Zhang, Tim Rostron, Harry Griffin, Stephen Taylor, Keyi Xu, Huiping Yan, Hao Wu, Ian James, Mina John, Tao Dong, and Sarah L. Rowland-Jones. High Frequency of HIV Mutations Associated with HLA-C Suggests Enhanced HLA-C-Restricted CTL Selective Pressure Associated with an AIDS-Protective Polymorphism. J. Immunol., 188(9):4663-4670, 1 May 2012. PubMed ID: 22474021. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health