HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 53545

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HXB2 Location Nef(120-128)
DNA(9154..9180)
Nef Epitope Map
Author Location Nef
Epitope YFPDWQDYT Epitope Alignment
YFPDWQDYT epitope logo
Epitope Name YT9
Subtype B
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A3, B57, B7, Cw6, Cw7
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, escape, characterizing CD8+ T cells, viral fitness and reversion

Notes

References

Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.


Displaying record number 54685

Download this epitope record as JSON.

HXB2 Location Nef(120-128)
DNA(9154..9180)
Nef Epitope Map
Author Location Nef(120-128)
Epitope YFPDWQDYT Epitope Alignment
YFPDWQDYT epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords HAART, ART, escape, viral fitness and reversion

Notes

References

Asquith2006 Becca Asquith, Charles T. T. Edwards, Marc Lipsitch, and Angela R. McLean. Inefficient Cytotoxic T Lymphocyte-Mediated Killing of HIV-1-Infected Cells In Vivo. PLoS Biol., 4(4):e90, Apr 2006. PubMed ID: 16515366. Show all entries for this paper.


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