HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 8 matching records:

Displaying record number 62315

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HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location Env(217-226)
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Show epitope variants
Epitope Name YL10
Subtype B
Species (MHC/HLA) human(C*01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords acute/early infection, mutation acquisition, viral fitness and reversion, viral replication

Notes

References

Troyer2009 Ryan M. Troyer, John McNevin, Yi Liu, Shao Chong Zhang, Randall W. Krizan, Awet Abraha, Denis M. Tebit, Hong Zhao, Santiago Avila, Michael A. Lobritz, M. Juliana McElrath, Sylvie Le Gall, James I. Mullins, and Eric J. Arts. Variable Fitness Impact of HIV-1 Escape Mutations to Cytotoxic T Lymphocyte (CTL) Response. PLoS Pathog., 5(4):e1000365, Apr 2009. PubMed ID: 19343217. Show all entries for this paper.


Displaying record number 55833

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HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location Env
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Epitope Name YL10
Subtype B
Species (MHC/HLA) human(C*01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords binding affinity

Notes

References

Cao2008 Jianhong Cao, John McNevin, Matthew McSweyn, Yi Liu, James I. Mullins, and M. Juliana McElrath. Novel Cytotoxic T-Lymphocyte Escape Mutation by a Three-Amino-Acid Insertion in the Human Immunodeficiency Virus Type 1 p6Pol and p6Gag Late Domain Associated with Drug Resistance. J. Virol., 82(1):495-502, Jan 2008. PubMed ID: 17942528. Show all entries for this paper.


Displaying record number 54163

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HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location gp120(217-226 HIV-MN)
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Show epitope variants
Epitope Name YL10
Subtype B
Species (MHC/HLA) human(C*01:02)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, mutation acquisition, optimal epitope

Notes

References

Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.


Displaying record number 59093

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HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location gp120(217-226)
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(C*01:02)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords viral fitness and reversion

Notes

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 61024

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HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location gp160(217-226)
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Subtype B
Species (MHC/HLA) human(C*01:02)
Immunogen HIV-1 infection
Patient MHC/HLA 10849: A*23:01, A*68:01, B*35:43, B*57:03, C*01:02, C*02:10
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 58152

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HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location gp120(217-226)
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Show epitope variants
Epitope Name YL10
Subtype B
Species (MHC/HLA) human(C*01:02)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection

Notes

References

Liu2011a Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, and James I. Mullins. Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection. PLoS One, 6(1):e15639, 2011. PubMed ID: 21283794. Show all entries for this paper.


Displaying record number 57084

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HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location gp120(217-226 DU422)
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Subtype B
Species (MHC/HLA) human(C*01:02)
Immunogen in vitro stimulation or selection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords dendritic cells

Notes

References

Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.


Displaying record number 57162

Download this epitope record as JSON.

HXB2 Location gp160(217-226)
gp120(217-226)
DNA(6873..6902)
gp160 Epitope Map
Author Location gp120(218-226)
Epitope YCAPAGFAIL Epitope Alignment
YCAPAGFAIL epitope logo
Epitope Name YL10
Subtype B
Species (MHC/HLA) human(Cw1)
Immunogen HIV-1 infection
Patient MHC/HLA A26, A32, B27, Cw1, Cw2
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HIV exposed persistently seronegative (HEPS), acute/early infection

Notes

References

Liu2009b Yi Liu, Amanda Woodward, Haiying Zhu, Thomas Andrus, John McNevin, Jean Lee, James I. Mullins, Lawrence Corey, M. Juliana McElrath, and Tuofu Zhu. Preinfection Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T Lymphocytes Failed to Prevent HIV Type 1 Infection from Strains Genetically Unrelated to Viruses in Long-Term Exposed Partners. J. Virol., 83(20):10821-10829, Oct 2009. PubMed ID: 19706711. Show all entries for this paper.


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