HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 15 matching records:

Displaying record number 60457

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(A*24)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60456

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(A*30)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60458

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(B*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54346

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name B15-WF9(Nef)
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 54581

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Show epitope variants
Epitope Name WF9
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection
Country United States
Experimental methods Intracellular cytokine staining, Other
Keywords rate of progression, escape, mutation acquisition

Notes

References

Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.


Displaying record number 60454

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 1967

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name Nef-WF9
Subtype B
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Patient MHC/HLA 01RCH50: A*2904, A*3002, B*1503, B*5802, Cw*0202, Cw*0602
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords HAART, ART, novel epitope

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 52558

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 52618

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Subtype B
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Patient MHC/HLA A*2301, B*1503, B*3501, Cw2, Cw7
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords binding affinity, acute/early infection, early-expressed proteins

Notes

References

Cao2003 Jianhong Cao, John McNevin, Sarah Holte, Lisa Fink, Lawrence Corey, and M. Juliana McElrath. Comprehensive Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Secreting CD8+ T Cells in Primary HIV-1 Infection. J. Virol., 77(12):6867-6878, Jun 2003. PubMed ID: 12768006. Show all entries for this paper.


Displaying record number 53916

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Subtype B
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Patient MHC/HLA A*0301, A*2301, B*0702, B*1503
Country United States
Experimental methods  
Keywords escape, acute/early infection

Notes

References

Bernardin2005 Flavien Bernardin, Denice Kong, Lorraine Peddada, Lee Ann Baxter-Lowe, and Eric Delwart. Human Immunodeficiency Virus Mutations During the First Month of Infection are Preferentially Found in Known Cytotoxic T-Lymphocyte Epitopes. J. Virol., 79(17):11523-11528, Sep 2005. PubMed ID: 16103205. Show all entries for this paper.


Displaying record number 58865

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Subtype A, B
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Country Australia
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, optimal epitope, HLA associated polymorphism

Notes

References

Keane2012 Niamh M. Keane, Steven G. Roberts, Coral-Ann M. Almeida, Tanya Krishnan, Abha Chopra, Emma Demaine, Rebecca Laird, Monika Tschochner, Jonathan M. Carlson, Simon Mallal, David Heckerman, Ian James, and Mina John. High-Avidity, High-IFN-gamma-Producing CD8 T-Cell Responses following Immune Selection during HIV-1 Infection. Immunol. Cell Biol., 90(2):224-234, Feb 2012. PubMed ID: 21577229. Show all entries for this paper.


Displaying record number 61023

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Subtype B
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Patient MHC/HLA 17543: A*0101, A*0202, B*0701, B*1503, Cw*0210, Cw*0702
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 60455

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(B*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60459

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(B*27)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 61208

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef
Epitope WRFDSRLAF Epitope Alignment
WRFDSRLAF epitope logo
Show epitope variants
Epitope Name WF9
Subtype B
Species (MHC/HLA) human(B*2705)
Immunogen HIV-1 infection
Experimental methods Other
Keywords review, escape, HLA associated polymorphism

Notes

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


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