HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 54542

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HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WKFDSRLAF Epitope Alignment
WKFDSRLAF epitope logo
Show epitope variants
Epitope Name WF9
Subtype B
Species (MHC/HLA) human(B*15:03)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection, assay or method development, mutation acquisition

Notes

References

Malhotra2007a Uma Malhotra, Fusheng Li, Jessica Nolin, Megan Allison, Hong Zhao, James I. Mullins, Steve Self, and M. Juliana McElrath. Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection. J. Virol., 81(10):5225-5237, May 2007. PubMed ID: 17329342. Show all entries for this paper.


Displaying record number 55075

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HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef
Epitope WKFDSRLAF Epitope Alignment
WKFDSRLAF epitope logo
Show epitope variants
Subtype B, C
Species (MHC/HLA) human(B*15:03)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, rate of progression, immunodominance

Notes

References

Frahm2006 Nicole Frahm, Photini Kiepiela, Sharon Adams, Caitlyn H. Linde, Hannah S. Hewitt, Kaori Sango, Margaret E. Feeney, Marylyn M. Addo, Mathias Lichterfeld, Matthew P. Lahaie, Eunice Pae, Alysse G. Wurcel, Timothy Roach, M Anne. St. John, Marcus Altfeld, Francesco M. Marincola, Corey Moore, Simon Mallal, Mary Carrington, David Heckerman, Todd M. Allen, James I. Mullins, Bette T. Korber, Philip J. R. Goulder, Bruce D. Walker, and Christian Brander. Control of Human Immunodeficiency Virus Replication by Cytotoxic T Lymphocytes Targeting Subdominant Epitopes. Nat. Immunol., 7(2):173-178, Feb 2006. PubMed ID: 16369537. Show all entries for this paper.


Displaying record number 57248

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HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef
Epitope WKFDSRLAF Epitope Alignment
WKFDSRLAF epitope logo
Show epitope variants
Epitope Name WF9
Subtype B
Species (MHC/HLA) human(B*15:03)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, CD8 T-cell Elispot granzyme B
Keywords acute/early infection

Notes

References

Malhotra2009 U. Malhotra, J. Nolin, H. Horton, F. Li, L. Corey, J. I. Mullins, and M. J. McElrath. Functional Properties and Epitope Characteristics of T-Cells Recognizing Natural HIV-1 Variants. Vaccine, 27(48):6678-6687, 12 Nov 2009. PubMed ID: 19747576. Show all entries for this paper.


Displaying record number 57961

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HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef(183-191)
Epitope WKFDSRLAF Epitope Alignment
WKFDSRLAF epitope logo
Show epitope variants
Epitope Name WF9
Subtype A, B
Species (MHC/HLA) human(B*15:03)
Immunogen HIV-1 infection
Country Australia
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, HLA associated polymorphism

Notes

References

Keane2012 Niamh M. Keane, Steven G. Roberts, Coral-Ann M. Almeida, Tanya Krishnan, Abha Chopra, Emma Demaine, Rebecca Laird, Monika Tschochner, Jonathan M. Carlson, Simon Mallal, David Heckerman, Ian James, and Mina John. High-Avidity, High-IFN-gamma-Producing CD8 T-Cell Responses following Immune Selection during HIV-1 Infection. Immunol. Cell Biol., 90(2):224-234, Feb 2012. PubMed ID: 21577229. Show all entries for this paper.


Displaying record number 55998

Download this epitope record as JSON.

HXB2 Location Nef(183-191)
DNA(9343..9369)
Nef Epitope Map
Author Location Nef
Epitope WKFDSRLAF Epitope Alignment
WKFDSRLAF epitope logo
Show epitope variants
Epitope Name WF9(Nef)
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity, chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


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