HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 24 matching records:

Displaying record number 60436

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(A*31)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60440

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(A*66)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Birk1998 M. Birk, A. Vahlne, A. Sonnerborg, and M. Sallberg. Nonsynonymous Mutations within the Human Immunodeficiency Virus Type 1 p17 Gene Are Clustered to Sequences Binding to the Host Human Leukocyte Antigen Class I Molecules. AIDS Res. Hum. Retroviruses, 14:241-248, 1998. PubMed ID: 9491914. Show all entries for this paper.


Displaying record number 1443

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 1565

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17(36-44 SF2)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 53044

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Koning2004 Fransje A. Koning, Christine A. Jansen, Jos Dekker, Richard A. Kaslow, Nicole Dukers, Debbie van Baarle, Maria Prins, and Hanneke Schuitemaker. Correlates of Resistance to HIV-1 Infection in Homosexual Men with High-Risk Sexual Behaviour. AIDS, 18(8):1117-1126, 21 May 2004. PubMed ID: 15166527. Show all entries for this paper.


Displaying record number 55039

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location  
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 56009

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9(p17)
Subtype B
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55215

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location  
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supertype, HLA cross-presentation, optimal epitope

Notes

References

Frahm2007b Nicole Frahm, Karina Yusim, Todd J. Suscovich, Sharon Adams, John Sidney, Peter Hraber, Hannah S. Hewitt, Caitlyn H. Linde, Daniel G. Kavanagh, Tonia Woodberry, Leah M. Henry, Kellie Faircloth, Jennifer Listgarten, Carl Kadie, Nebojsa Jojic, Kaori Sango, Nancy V. Brown, Eunice Pae, M. Tauheed Zaman, Florian Bihl, Ashok Khatri, Mina John, Simon Mallal, Francesco M. Marincola, Bruce D . Walker, Alessandro Sette, David Heckerman, Bette T. Korber, and Christian Brander. Extensive HLA Class I Allele Promiscuity among Viral CTL Epitopes. Eur. J. Immunol., 37(9):2419-2433, Sep 2007. PubMed ID: 17705138. Show all entries for this paper.


Displaying record number 1996

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name Gag-WF9; p17-WF9
Subtype B
Species (MHC/HLA) human(B*35)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HAART, ART

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 55

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17(35-43 LAI)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Subtype B
Species (MHC/HLA) human(B*3501)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Goulder1997a P. J. Goulder, A. Edwards, R. E. Phillips, and A. J. McMichael. Identification of a Novel HLA-B*3501-Restricted Cytotoxic T Lymphocyte Epitope Using Overlapping Peptides. AIDS, 11(7):930-932, 1997. PubMed ID: 9189221. Show all entries for this paper.


Displaying record number 1200

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17(36-44 LAI)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Subtype B
Species (MHC/HLA) human(B*3501)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Goulder1997f P. J. Goulder, M. Bunce, G. Luzzi, R. E. Phillips, and A. J. McMichael. Potential Underestimation of HLA-C-Restricted Cytotoxic T-Lymphocyte Responses. AIDS, 11(15):1884-1886, 1997. PubMed ID: 9412710. Show all entries for this paper.

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 57478

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Subtype B
Species (MHC/HLA) human(B*3501)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Cytokine production, Flow cytometric T-cell cytokine assay, HLA binding
Keywords computational epitope prediction

Notes

References

Westrop2009 Samantha J. Westrop, Nathali Grageda, and Nesrina Imami. Novel Approach to Recognition of Predicted HIV-1 Gag B3501-Restricted CD8 T-Cell Epitopes by HLA-B3501+ Patients: Confirmation by Quantitative ELISpot Analyses and Characterisation Using Multimers. J. Immunol. Methods, 341(1-2):76-85, 28 Feb 2009. PubMed ID: 19056394. Show all entries for this paper.


Displaying record number 60673

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Subtype B
Species (MHC/HLA) human(B*3501)
Immunogen HIV-1 infection
Patient MHC/HLA S2:
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords dendritic cells, assay or method development, memory cells

Notes

References

Smith2016 Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, and Charles R. Rinaldo. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. MBio, 7(3), 31 May 2016. PubMed ID: 27247230. Show all entries for this paper.


Displaying record number 60438

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(B*3502, B*3503, B*5301)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60434

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(B*4201)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60433

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(B*51)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60435

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(C*04)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60439

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(C*08)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60441

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(C*12)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60437

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Epitope Name WF9
Species (MHC/HLA) human(C*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53887

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17(36-44)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Subtype C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country India
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, immunodominance

Notes

References

Thakar2005 Madhuri R. Thakar, Leena S. Bhonge, Samir K. Lakhashe, U. Shankarkumar, Suvarna S. Sane, Smita S. Kulkarni, Bharati A. Mahajan, and Ramesh S. Paranjape. Cytolytic T Lymphocytes (CTLs) from HIV-1 Subtype C-Infected Indian Patients Recognize CTL Epitopes From a Conserved Immunodominant Region of HIV-1 Gag and Nef. J. Infect. Dis., 192(5):749-759, 1 Sep 2005. PubMed ID: 16088824. Show all entries for this paper.


Displaying record number 1163

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location p17( SF2)
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons, immunodominance

Notes

References

Goulder2000 P. J. Goulder, C. Brander, K. Annamalai, N. Mngqundaniso, U. Govender, Y. Tang, S. He, K. E. Hartman, C. A. O'Callaghan, G. S. Ogg, M. A. Altfeld, E. S. Rosenberg, H. Cao, S. A. Kalams, M. Hammond, M. Bunce, S. I. Pelton, S. A. Burchett, K. McIntosh, H. M. Coovadia, and B. D. Walker. Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children. J. Virol., 74:5679-90, 2000. PubMed ID: 10823876. Show all entries for this paper.


Displaying record number 57032

HXB2 Location Gag(36-44)
p17(36-44)
DNA(895..921)
Gag Epitope Map
Author Location Gag
Epitope WASRELERF Epitope Alignment
WASRELERF epitope logo
Subtype B, CRF01_AE
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


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