HIV molecular immunology database
Found 9 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(274-282) | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Epitope Name | VI9 | |
Species (MHC/HLA) | human(B*07) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(274-282) | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Subtype | A, D | |
Species (MHC/HLA) | human(B*07:02) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 2127: A*01:01, A*03:01, B*07:02, B*41:01, C*07:01, C*07:23 | |
Country | Kenya | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other, Tetramer binding | |
Keywords | subtype comparisons, HIV exposed persistently seronegative (HEPS), assay or method development |
Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(274-282) | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Epitope Name | VI9 | |
Species (MHC/HLA) | human(B*52) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(274-282) | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Epitope Name | VI9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | ||
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Epitope Name | VI9 | |
Species (MHC/HLA) | human(C*18) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | Gag | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Epitope Name | VI9-Cw18 | |
Subtype | B, F | |
Species (MHC/HLA) | human(C*18) | |
Immunogen | HIV-1 infection | |
Country | Argentina | |
Experimental methods | ||
Keywords | dynamics, escape, HLA associated polymorphism |
Dilernia2008 Dario Alberto Dilernia, Leandro Jones, Sabrina Rodriguez, Gabriela Turk, Andrea E Rubio, Sandra Pampuro, Manuel Gomez-Carrillo, Christian Bautista, Gabriel Deluchi, Jorge Benetucci, María Beatriz Lasala, Leonardo Lourtau, Marcelo Horacio Losso, Héctor Perez, Pedro Cahn, and Horacio Salomón. HLA-Driven Convergence of HIV-1 Viral Subtypes B and F Toward the Adaptation to Immune Responses in Human Populations. PLoS ONE, 3(10):e3429, 2008. PubMed ID: 18941505. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(C*18:01) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, optimal epitope |
Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | p24(142-150) | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Species (MHC/HLA) | human(C*18:01) | |
Immunogen | peptide-HLA interaction | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining | |
Keywords | optimal epitope |
Honeyborne2006 Isobella Honeyborne, Almas Rathod, Rico Buchli, Dhanwanthie Ramduth, Eshia Moodley, Prinisha Rathnavalu, Senica Chetty, Cheryl Day, Christian Brander, William Hildebrand, Bruce D. Walker, Photini Kiepiela, and Philip J. R. Goulder. Motif Inference Reveals Optimal CTL Epitopes Presented by HLA Class I Alleles Highly Prevalent in Southern Africa. J. Immunol., 176(8):4699-4705, 15 Apr 2006. PubMed ID: 16585563. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(274-282) p24(142-150) DNA(1609..1635) |
Gag Epitope Map |
---|---|---|
Author Location | p24(274-282) | |
Epitope |
VRMYSPVSI
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.