HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 22 matching records:

Displaying record number 60416

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(A*29)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60413

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(A*32)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60415

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(A*34)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60412

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 57583

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Subtype B
Species (MHC/HLA) (B*27)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Dinges2010 Warren L. Dinges, Julia Richardt, David Friedrich, Emilie Jalbert, Yi Liu, Claire E. Stevens, Janine Maenza, Ann C. Collier, Daniel E. Geraghty, Jeremy Smith, Zoe Moodie, James I. Mullins, M. Juliana McElrath, and Helen Horton. Virus-Specific CD8+ T-Cell Responses Better Define HIV Disease Progression than HLA Genotype. J. Virol., 84(9):4461-4468, May 2010. PubMed ID: 20147397. Show all entries for this paper.


Displaying record number 58497

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Subtype B
Species (MHC/HLA) human(B*27)
Immunogen HIV-1 infection
Country Canada
Experimental methods Other
Keywords characterizing CD8+ T cells, elite controllers

Notes

References

Peretz2011 Yoav Peretz, Olivia Marra, Réjean Thomas, Danielle Legault, Pierre Côté, Mohamed-Rachid Boulassel, Danielle Rouleau, Jean-Pierre Routy, Rafick-Pierre Sékaly, Christos M Tsoukas, Cécile Tremblay, and Nicole F. Bernard. Relative Contribution of HIV-Specific Functional Lymphocyte Subsets Restricted by Protective and Non-Protective HLA Alleles. Viral Immunol, 24(3):189-198, Jun 2011. PubMed ID: 21668360. Show all entries for this paper.


Displaying record number 60408

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(B*27)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 61020

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Subtype B
Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection
Patient MHC/HLA 53617: A*02:01, A*02:05, B*27:05, B*49:01, C*02:02, C*07:01; 79379: A*01:01, B*27:05:02G, B*52:01:01G, C*02:02:02, C*12:02:01G
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 52562

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 55484

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Subtype B
Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Tetramer binding
Keywords superinfection

Notes

References

Streeck2008a Hendrik Streeck, Bin Li, Art F. Y. Poon, Arne Schneidewind, Adrianne D. Gladden, Karen A. Power, Demetre Daskalakis, Suzane Bazner, Rosario Zuniga, Christian Brander, Eric S. Rosenberg, Simon D. W. Frost, Marcus Altfeld, and Todd M. Allen. Immune-Driven Recombination and Loss of Control after HIV Superinfection. J. Exp. Med., 205(8):1789-1796, 4 Aug 2008. PubMed ID: 18625749. Show all entries for this paper.


Displaying record number 62473

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location  
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Subtype B
Species (MHC/HLA) human(B*27:02)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods Other, Tetramer binding
Keywords immunodominance, chronic infection, protective allele

Notes

References

Adland2018 Emily Adland, Matilda Hill, Nora Lavandier, Anna Csala, Anne Edwards, Fabian Chen, Marek Radkowski, Justyna D. Kowalska, Dimitrios Paraskevis, Angelos Hatzakis, Humberto Valenzuela-Ponce, Katja Pfafferott, Ian Williams, Pierre Pellegrino, Persephone Borrow, Masahiko Mori, Jürgen Rockstroh, Julia G. Prado, Beatriz Mothe, Judith Dalmau, Javier Martinez-Picado, Gareth Tudor-Williams, John Frater, Anette Stryhn, Soren Buus, Gustavo Reyes Teran, Simon Mallal, Mina John, Susan Buchbinder, Gregory Kirk, Jeffrey Martin, Nelson Michael, Jacques Fellay, Steve Deeks, Bruce Walker, Santiago Avila-Rios, David Cole, Christian Brander, Mary Carrington, and Philip Goulder. Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J. Virol., 92(4), 15 Feb 2018. PubMed ID: 29167337. Show all entries for this paper.


Displaying record number 61209

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Show epitope variants
Epitope Name VL9
Subtype B
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Experimental methods Other
Keywords review, escape, HLA associated polymorphism

Notes

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


Displaying record number 62472

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location  
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Subtype B
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods Other, Tetramer binding
Keywords immunodominance, chronic infection, protective allele

Notes

References

Adland2018 Emily Adland, Matilda Hill, Nora Lavandier, Anna Csala, Anne Edwards, Fabian Chen, Marek Radkowski, Justyna D. Kowalska, Dimitrios Paraskevis, Angelos Hatzakis, Humberto Valenzuela-Ponce, Katja Pfafferott, Ian Williams, Pierre Pellegrino, Persephone Borrow, Masahiko Mori, Jürgen Rockstroh, Julia G. Prado, Beatriz Mothe, Judith Dalmau, Javier Martinez-Picado, Gareth Tudor-Williams, John Frater, Anette Stryhn, Soren Buus, Gustavo Reyes Teran, Simon Mallal, Mina John, Susan Buchbinder, Gregory Kirk, Jeffrey Martin, Nelson Michael, Jacques Fellay, Steve Deeks, Bruce Walker, Santiago Avila-Rios, David Cole, Christian Brander, Mary Carrington, and Philip Goulder. Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J. Virol., 92(4), 15 Feb 2018. PubMed ID: 29167337. Show all entries for this paper.


Displaying record number 57999

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location  
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Subtype C
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Country South Africa, United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Tetramer binding
Keywords computational epitope prediction, optimal epitope

Notes

References

ErupLarsen2011 Malene Erup Larsen, Henrik Kloverpris, Anette Stryhn, Catherine K. Koofhethile, Stuart Sims, Thumbi Ndung'u, Philip Goulder, Søren Buus, and Morten Nielsen. HLArestrictor---A Tool for Patient-Specific Predictions of HLA Restriction Elements and Optimal Epitopes within Peptides. Immunogenetics, 63(1):43-55, Jan 2011. PubMed ID: 21079948. Show all entries for this paper.


Displaying record number 57770

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Subtype B
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining, Other
Keywords rate of progression

Notes

References

Payne2010 Rebecca P. Payne, Henrik Kløverpris, Jonah B. Sacha, Zabrina Brumme, Chanson Brumme, Søren Buus, Stuart Sims, Stephen Hickling, Lynn Riddell, Fabian Chen, Graz Luzzi, Anne Edwards, Rodney Phillips, Julia G. Prado, and Philip J. R. Goulder. Efficacious Early Antiviral Activity of HIV Gag- and Pol-Specific HLA-B*2705-Restricted CD8+ T Cells. J. Virol., 84(20):10543-10557, Oct 2010. PubMed ID: 20686036. Show all entries for this paper.


Displaying record number 59032

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39 NL4-3)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9Vpr
Subtype B
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Patient MHC/HLA R035: A*02:01, A*24:02, B*27:05, B*44:02, C*02:02, C*05:01
Country United Kingdom
Experimental methods Intracellular cytokine staining, Other
Keywords cell-line isolated antibody

Notes

References

Kloverpris2013 Henrik N. Kløverpris, Rebecca P. Payne, Jonah B. Sacha, Jane T. Rasaiyaah, Fabian Chen, Masafumi Takiguchi, Otto O. Yang, Greg J. Towers, Philip Goulder, and Julia G. Prado. Early Antigen Presentation of Protective HIV-1 KF11Gag and KK10Gag Epitopes from Incoming Viral Particles Facilitates Rapid Recognition of Infected Cells by Specific CD8+ T Cells. J. Virol., 87(5):2628-2638, Mar 2013. PubMed ID: 23255798. Show all entries for this paper.


Displaying record number 58993

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Subtype B
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Country Argentina
Experimental methods Other
Keywords mutation acquisition

Notes

References

Bartha2013 István Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. McLaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio López-Galíndez, Concepción Casado, Andri Rauch, Huldrych F. Günthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltán Kutalik, Todd M. Allen, Viktor Müller, P. Richard Harrigan, David Heckerman, Amalio Telenti, and Jacques Fellay. A Genome-to-Genome Analysis of Associations between Human Genetic Variation, HIV-1 Sequence Diversity, and Viral Control. eLife, 2:e01123, 2013. PubMed ID: 24171102. Show all entries for this paper.


Displaying record number 60414

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(B*35:02, B*35:03, B*53:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60409

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60410

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60411

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Epitope Name VL9
Species (MHC/HLA) human(B*81)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55799

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HXB2 Location Vpr(31-39)
DNA(5649..5675)
Vpr Epitope Map
Author Location Vpr(31-39)
Epitope VRHFPRIWL Epitope Alignment
VRHFPRIWL epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords computational epitope prediction, HLA associated polymorphism

Notes

References

Srinivasan2008 Alagarsamy Srinivasan, Velpandi Ayyavoo, Sundarasamy Mahalingam, Aarthi Kannan, Anne Boyd, Debduti Datta, Vaniambadi S. Kalyanaraman, Anthony Cristillo, Ronald G. Collman, Nelly Morellet, Bassel E. Sawaya, and Ramachandran Murali. A Comprehensive Analysis of the Naturally Occurring Polymorphisms in HIV-1 Vpr: Potential Impact on CTL Epitopes. Virol. J., 5:99, 2008. PubMed ID: 18721481. Show all entries for this paper.


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