HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 7 matching records:

Displaying record number 60403

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HXB2 Location Gag(135-143)
p24(3-11)
DNA(1192..1218)
Gag Epitope Map
Author Location Gag(135-143)
Epitope VQNLQGQMV Epitope Alignment
VQNLQGQMV epitope logo
Epitope Name VV9
Species (MHC/HLA) human(B*13)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54582

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HXB2 Location Gag(135-143)
p24(3-11)
DNA(1192..1218)
Gag Epitope Map
Author Location Gag(135-143)
Epitope VQNLQGQMV Epitope Alignment
VQNLQGQMV epitope logo
Subtype B, C
Species (MHC/HLA) human(B*13)
Immunogen HIV-1 infection
Patient MHC/HLA A*03:01, A*30:01, B*13:01, B*14:02, C*06:02, C*08:02
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords epitope processing, escape, mutation acquisition, viral fitness and reversion, HLA associated polymorphism

Notes

References

Honeyborne2007 Isobella Honeyborne, Andrew Prendergast, Florencia Pereyra, Alasdair Leslie, Hayley Crawford, Rebecca Payne, Shabashini Reddy, Karen Bishop, Eshia Moodley, Kriebashnie Nair, Mary van der Stok, Noel McCarthy, Christine M. Rousseau, Marylyn Addo, James I. Mullins, Christian Brander, Photini Kiepiela, Bruce D. Walker, and Philip J. R. Goulder. Control of Human Immunodeficiency Virus Type 1 Is Associated with HLA-B*13 and Targeting of Multiple Gag-Specific CD8+ T-Cell Epitopes. J. Virol., 81(7):3667-3672, Apr 2007. PubMed ID: 17251285. Show all entries for this paper.


Displaying record number 54089

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HXB2 Location Gag(135-143)
p24(3-11)
DNA(1192..1218)
Gag Epitope Map
Author Location  
Epitope VQNLQGQMV Epitope Alignment
VQNLQGQMV epitope logo
Epitope Name VV9
Species (MHC/HLA) human(B*13)
Immunogen  
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 55984

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HXB2 Location Gag(135-143)
p24(3-11)
DNA(1192..1218)
Gag Epitope Map
Author Location p24
Epitope VQNLQGQMV Epitope Alignment
VQNLQGQMV epitope logo
Epitope Name VV9(p24)
Subtype B
Species (MHC/HLA) human(B13)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 58784

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HXB2 Location Gag(135-143)
p24(3-11)
DNA(1192..1218)
Gag Epitope Map
Author Location p24(135-143)
Epitope VQNLQGQMV Epitope Alignment
VQNLQGQMV epitope logo
Species (MHC/HLA) human(B*13:02)
Immunogen  
Experimental methods  
Keywords review

Notes

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.


Displaying record number 58438

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HXB2 Location Gag(135-143)
p24(3-11)
DNA(1192..1218)
Gag Epitope Map
Author Location p24(3-11)
Epitope VQNLQGQMV Epitope Alignment
VQNLQGQMV epitope logo
Subtype A1
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Proliferation
Keywords assay or method development, characterizing CD8+ T cells

Notes

References

Richmond2011 Meika Richmond, Lyle R. McKinnon, Sandra A. Koesters Kiazyk, Charles Wachihi, Makobu Kimani, Joshua Kimani, Francis A. Plummer, and T. Blake Ball. Epitope Mapping of HIV-Specific CD8+ T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function. J. Virol., 85(3):1275-1286, Feb 2011. PubMed ID: 21084478. Show all entries for this paper.


Displaying record number 62783

Download this epitope record as JSON.

HXB2 Location Gag(135-143)
p24(3-11)
DNA(1192..1218)
Gag Epitope Map
Author Location p24(135-143)
Epitope VQNLQGQMV Epitope Alignment
VQNLQGQMV epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


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