HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 56200

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HXB2 Location Rev(71-78)
DNA(8513..8536)
Rev Epitope Map
Author Location Rev(75-)
Epitope VPLQLPPL Epitope Alignment
VPLQLPPL epitope logo
Species (MHC/HLA) human(B*07:02)
Immunogen vaccine
Country Botswana, United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, polyepitope
Vaccine strain multiple epitope immunogen

Notes

References

Gorse2008a Geoffrey J. Gorse, Lindsey R. Baden, Margaret Wecker, Mark J. Newman, Guido Ferrari, Kent J. Weinhold, Brian D. Livingston, Tonya L. Villafana, Hongli Li, Elizabeth Noonan, Nina D. Russell, and HIV Vaccine Trials Network. Safety and Immunogenicity of Cytotoxic T-Lymphocyte Poly-Epitope, DNA Plasmid (EP HIV-1090) Vaccine in Healthy, Human Immunodeficiency Virus Type 1 (HIV-1)-Uninfected Adults. Vaccine, 26(2):215-223, 10 Jan 2008. PubMed ID: 18055072. Show all entries for this paper.


Displaying record number 57643

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HXB2 Location Rev(71-78)
DNA(8513..8536)
Rev Epitope Map
Author Location Rev(71-78)
Epitope VPLQLPPL Epitope Alignment
VPLQLPPL epitope logo
Epitope Name Rev71-11
Subtype B
Species (MHC/HLA) human(B*51:01)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords rate of progression

Notes

References

Kawashima2010 Yuka Kawashima, Nozomi Kuse, Hiroyuki Gatanaga, Takuya Naruto, Mamoru Fujiwara, Sachi Dohki, Tomohiro Akahoshi, Katsumi Maenaka, Philip Goulder, Shinichi Oka, and Masafumi Takiguchi. Long-Term Control of HIV-1 in Hemophiliacs Carrying Slow-Progressing Allele HLA-B*5101. J. Virol., 84(14):7151-7160, Jul 2010. PubMed ID: 20410273. Show all entries for this paper.


Displaying record number 56543

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HXB2 Location Rev(71-78)
DNA(8513..8536)
Rev Epitope Map
Author Location Env
Epitope VPLQLPPL Epitope Alignment
VPLQLPPL epitope logo
Epitope Name Env259
Subtype B
Species (MHC/HLA) human(B7)
Immunogen vaccine
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, polyepitope
Vaccine component other

Notes

References

Wilson2008 Cara C. Wilson, Mark J. Newman, Brian D. Livingston, Samantha MaWhinney, Jeri E. Forster, Jim Scott, Robert T. Schooley, and Constance A. Benson. Clinical Phase 1 Testing of the Safety and Immunogenicity of an Epitope-Based DNA Vaccine in Human Immunodeficiency Virus Type 1-Infected Subjects Receiving Highly Active Antiretroviral Therapy. Clin. Vaccine Immunol., 15(6):986-994, Jun 2008. PubMed ID: 18400976. Show all entries for this paper.


Displaying record number 56548

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HXB2 Location Rev(71-78)
DNA(8513..8536)
Rev Epitope Map
Author Location Rev
Epitope VPLQLPPL Epitope Alignment
VPLQLPPL epitope logo
Epitope Name Rev75
Subtype B
Species (MHC/HLA) human(B7)
Immunogen vaccine
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, polyepitope
Vaccine component other

Notes

References

Wilson2008 Cara C. Wilson, Mark J. Newman, Brian D. Livingston, Samantha MaWhinney, Jeri E. Forster, Jim Scott, Robert T. Schooley, and Constance A. Benson. Clinical Phase 1 Testing of the Safety and Immunogenicity of an Epitope-Based DNA Vaccine in Human Immunodeficiency Virus Type 1-Infected Subjects Receiving Highly Active Antiretroviral Therapy. Clin. Vaccine Immunol., 15(6):986-994, Jun 2008. PubMed ID: 18400976. Show all entries for this paper.


Displaying record number 56523

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HXB2 Location Rev(71-78)
DNA(8513..8536)
Rev Epitope Map
Author Location Rev
Epitope VPLQLPPL Epitope Alignment
VPLQLPPL epitope logo
Epitope Name Rev75
Subtype A, B, C, D
Species (MHC/HLA) human, mouse(B7 supertype)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords binding affinity, supertype, vaccine-induced immune responses, HLA cross-presentation

Notes

References

Wilson2003 Cara C. Wilson, Denise McKinney, Michelle Anders, Samantha MaWhinney, Jeri Forster, Claire Crimi, Scott Southwood, Alessandro Sette, Robert Chesnut, Mark J Newman, and Brian D Livingston. Development of a DNA Vaccine Designed to Induce Cytotoxic T Lymphocyte Responses to Multiple Conserved Epitopes in HIV-1. J. Immunol., 171(10):5611-5623, 15 Nov 2003. PubMed ID: 14607970. Show all entries for this paper.


Displaying record number 58213

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HXB2 Location Rev(71-78)
DNA(8513..8536)
Rev Epitope Map
Author Location Rev(71- CDC-451)
Epitope VPLQLPPL Epitope Alignment
VPLQLPPL epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen computer prediction
Experimental methods  
Keywords T-cell crossreactivity to human proteins

Notes

References

Lucchese2011 Guglielmo Lucchese, Angela Stufano, Michele Calabro, and Darja Kanduc. Charting the Peptide Crossreactome between HIV-1 and the Human Proteome. Front. Biosci. (Elite Ed.), 3E:1385-1400, 2011. PubMed ID: 21622144. Show all entries for this paper.


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