HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 23 matching records:

Displaying record number 1984

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location p24
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name Gag-VV9; p24-VV9
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HAART, ART

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 54558

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(363-370)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country United States
Experimental methods Intracellular cytokine staining, Other
Keywords rate of progression, escape, mutation acquisition

Notes

References

Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.


Displaying record number 60377

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(362-370)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name VV9
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53843

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location p24-p2p7p1p6(362-370)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Show epitope variants
Epitope Name VV9
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Patient MHC/HLA M-1005: A*02, A*32, B*07, B*40, C*03, C*07; P-1026: A*24, A*32, B*07, B*18, C*07
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords responses in children, mother-to-infant transmission, escape, acute/early infection, viral fitness and reversion

Notes

References

Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.


Displaying record number 1305

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(386-)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name Gag-386
Species (MHC/HLA) human(A*02:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords binding affinity, supertype, computational epitope prediction, immunodominance, HLA cross-presentation

Notes

References

Altfeld2001 M. A. Altfeld, B. Livingston, N. Reshamwala, P. T. Nguyen, M. M. Addo, A. Shea, M. Newman, J. Fikes, J. Sidney, P. Wentworth, R. Chesnut, R. L. Eldridge, E. S. Rosenberg, G. K. Robbins, C. Brander, P. E. Sax, S. Boswell, T. Flynn, S. Buchbinder, P. J. Goulder, B. D. Walker, A. Sette, and S. A. Kalams. Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif. J. Virol., 75(3):1301-11, Feb 2001. URL: http://jvi.asm.org/cgi/content/full/75/3/1301. PubMed ID: 11152503. Show all entries for this paper.


Displaying record number 53071

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Show epitope variants
Epitope Name Gag 386
Subtype M group
Species (MHC/HLA) human, humanized mouse, mouse(A*02:01)
Immunogen in vitro stimulation or selection, vaccine
Experimental methods Cytokine production, T-cell Elispot
Keywords subtype comparisons, computational epitope prediction, escape, TCR usage, variant cross-reactivity

Vaccine Details

Vaccine type DNA, peptide
Adjuvant Incomplete Freund's Adjuvant (IFA)

Notes

References

McKinney2004 Denise M. McKinney, Rhonda Skvoretz, Brian D. Livingston, Cara C. Wilson, Michelle Anders, Robert W. Chesnut, Alessandro Sette, Max Essex, Vladimir Novitsky, and Mark J. Newman. Recognition of Variant HIV-1 Epitopes from Diverse Viral Subtypes by Vaccine-Induced CTL. J. Immunol., 173(3):1941-1950, 1 Aug 2004. PubMed ID: 15265928. Show all entries for this paper.


Displaying record number 56186

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(386-)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Species (MHC/HLA) human(A*02:01)
Immunogen vaccine
Country Botswana, United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, polyepitope
Vaccine strain multiple epitope immunogen

Notes

References

Gorse2008a Geoffrey J. Gorse, Lindsey R. Baden, Margaret Wecker, Mark J. Newman, Guido Ferrari, Kent J. Weinhold, Brian D. Livingston, Tonya L. Villafana, Hongli Li, Elizabeth Noonan, Nina D. Russell, and HIV Vaccine Trials Network. Safety and Immunogenicity of Cytotoxic T-Lymphocyte Poly-Epitope, DNA Plasmid (EP HIV-1090) Vaccine in Healthy, Human Immunodeficiency Virus Type 1 (HIV-1)-Uninfected Adults. Vaccine, 26(2):215-223, 10 Jan 2008. PubMed ID: 18055072. Show all entries for this paper.


Displaying record number 56527

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name Gag386
Subtype B
Species (MHC/HLA) human(A2)
Immunogen vaccine
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, polyepitope
Vaccine component other

Notes

References

Wilson2008 Cara C. Wilson, Mark J. Newman, Brian D. Livingston, Samantha MaWhinney, Jeri E. Forster, Jim Scott, Robert T. Schooley, and Constance A. Benson. Clinical Phase 1 Testing of the Safety and Immunogenicity of an Epitope-Based DNA Vaccine in Human Immunodeficiency Virus Type 1-Infected Subjects Receiving Highly Active Antiretroviral Therapy. Clin. Vaccine Immunol., 15(6):986-994, Jun 2008. PubMed ID: 18400976. Show all entries for this paper.


Displaying record number 52666

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(362-)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Show epitope variants
Epitope Name Gag362(9L)
Species (MHC/HLA) human, transgenic mouse(A2)
Immunogen HIV-1 infection, vaccine
Experimental methods Chromium-release assay, Flow cytometric T-cell cytokine assay, T-cell Elispot
Keywords binding affinity, subtype comparisons, computational epitope prediction

Vaccine Details

Vaccine type peptide
Adjuvant Incomplete Freund's Adjuvant (IFA)

Notes

References

Corbet2003 Sylvie Corbet, Henrik Vedel Nielsen, Lasse Vinner, Sanne Lauemoller, Dominic Therrien, Sheila Tang, Gitte Kronborg, Lars Mathiesen, Paul Chaplin, Søren Brunak, Søren Buus, and Anders Fomsgaard. Optimization and Immune Recognition of Multiple Novel Conserved HLA-A2, Human Immunodeficiency Virus Type 1-Specific CTL Epitopes. J. Gen. Virol., 84(Pt 9):2409-2421, Sep 2003. PubMed ID: 12917462. Show all entries for this paper.


Displaying record number 53582

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location p24(230-238)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Subtype B
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, HLA binding
Keywords acute/early infection, optimal epitope

Notes

References

Altfeld2005a Marcus Altfeld, Todd M. Allen, Elizabeth T. Kalife, Nicole Frahm, Marylyn M. Addo, Bianca R. Mothe, Almas Rathod, Laura L. Reyor, Jason Harlow, Xu G. Yu, Beth Perkins, Loren K. Robinson, John Sidney, Galit Alter, Mathias Lichterfeld, Alessandro Sette, Eric S. Rosenberg, Philip J. R. Goulder, Christian Brander, and Bruce D. Walker. The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail To Prime Cytotoxic T-Lymphocyte Responses against an Otherwise Immunodominant HLA-A2-Restricted Epitope: Implications for Vaccine Design. J. Virol., 79(8):5000-5005, Apr 2005. PubMed ID: 15795285. Show all entries for this paper.


Displaying record number 54233

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location p24
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name A2-VV9(gp24)
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 54855

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location p2p7p1p6(362-370 Henan isolate)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Subtype B
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Gong2006 Xiaoyan Gong, Xien Gui, Yuxia Zhang, and Po Tien. Screening for CD8 Cytotoxic T Lymphocytes Specific for Gag of Human Immunodeficiency Virus Type 1 Subtype B' Henan Isolate from China and Identification of Novel Epitopes Restricted by the HLA-A2 and HLA-A11 Alleles. J. Gen. Virol., 87(Pt 1):151-158, Jan 2006. PubMed ID: 16361427. Show all entries for this paper.


Displaying record number 55371

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location  
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Show epitope variants
Epitope Name Gag 362(9V)
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Denmark
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords variant cross-reactivity

Notes

References

Thorn2007 Mette Thorn, Sheila Tang, Dominic Therrien, Henrik Kløverpris, Lasse Vinner, Gitte Kronborg, Jan Gerstoft, Sylvie Corbet, and Anders Fomsgaard. Sequence Conservation of Subdominant HLA-A2-Binding CTL Epitopes in HIV-1 Clinical Isolates and CD8+ T-Lymphocyte Cross-Recognition May Explain the Immune Reaction in Infected Individuals. APMIS, 115(6):757-768, Jun 2007. PubMed ID: 17550385. Show all entries for this paper.


Displaying record number 56059

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(362-)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Show epitope variants
Epitope Name Gag362(9V)
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Denmark
Experimental methods Flow cytometric T-cell cytokine assay
Keywords rate of progression, escape, acute/early infection

Notes

References

Fomsgaard2008 Anders Fomsgaard, Lasse Vinner, Dominic Therrien, Louise B. Jørgensen, Claus Nielsen, Lars Mathiesen, Court Pedersen, and Sylvie Corbet. Full-Length Characterization of A1/D Intersubtype Recombinant Genomes from a Therapy-Induced HIV Type 1 Controller during Acute Infection and His Noncontrolling Partner. AIDS Res. Hum. Retroviruses, 24(3):463-472, Mar 2008. PubMed ID: 18373434. Show all entries for this paper.


Displaying record number 60376

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(362-370)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name VV9
Species (MHC/HLA) human(A*29)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55741

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name Gag386
Subtype A, B, C, D
Species (MHC/HLA) human, mouse(A2 supertype)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords binding affinity, supertype, vaccine-induced immune responses, HLA cross-presentation

Notes

References

Wilson2003 Cara C. Wilson, Denise McKinney, Michelle Anders, Samantha MaWhinney, Jeri Forster, Claire Crimi, Scott Southwood, Alessandro Sette, Robert Chesnut, Mark J Newman, and Brian D Livingston. Development of a DNA Vaccine Designed to Induce Cytotoxic T Lymphocyte Responses to Multiple Conserved Epitopes in HIV-1. J. Immunol., 171(10):5611-5623, 15 Nov 2003. PubMed ID: 14607970. Show all entries for this paper.


Displaying record number 1587

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(397-405)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Species (MHC/HLA) human(A2 supertype)
Immunogen HIV-1 infection
Experimental methods  
Keywords supertype, rate of progression

Notes

References

Propato2001 A. Propato, E. Schiaffella, E. Vicenzi, V. Francavilla, L. Baloni, M. Paroli, L. Finocchi, N. Tanigaki, S. Ghezzi, R. Ferrara, R. Chesnut, B. Livingston, A. Sette, R. Paganelli, F. Aiuti, G. Poli, and V. Barnaba. Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity. Hum. Immunol., 62(6):561-76, Jun 2001. PubMed ID: 11390031. Show all entries for this paper.


Displaying record number 60378

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(362-370)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name VV9
Species (MHC/HLA) human(A*69)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60375

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(362-370)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name VV9
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60379

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag(362-370)
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Epitope Name VV9
Species (MHC/HLA) human(C*16)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 58041

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA A*02:01, A*43:01, B*40:01, B*53:01, C*03:04, C*04:01
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


Displaying record number 57027

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Subtype C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


Displaying record number 61340

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HXB2 Location Gag(362-370)
p24(230)-p2p7p1p6(7)
DNA(1873..1899)
Gag Epitope Map
Author Location Gag
Epitope VLAEAMSQV Epitope Alignment
VLAEAMSQV epitope logo
Species (MHC/HLA) human
Immunogen vaccine
Country Australia, Brazil, Canada, Dominican Republic, Haiti, Jamaica, Peru, Puerto Rico, United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, assay or method development, optimal epitope

Vaccine Details

Vaccine type adenovirus type 5 (Ad5)
Vaccine component Gag, Nef, Pol

Notes

References

Fiore-Gartland2016 Andrew Fiore-Gartland, Bryce A. Manso, David P. Friedrich, Erin E. Gabriel, Greg Finak, Zoe Moodie, Tomer Hertz, Stephen C. De Rosa, Nicole Frahm, Peter B. Gilbert, and M Juliana McElrath. Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials. PLoS One, 11(2):e0147812, 2016. PubMed ID: 26863315. Show all entries for this paper.


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