HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 15 matching records:

Displaying record number 60368

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location Gag(168-175)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Species (MHC/HLA) human(B*1516)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60367

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location Gag(168-175)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Species (MHC/HLA) human(B*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60366

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location Gag(168-175)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Species (MHC/HLA) human(C*01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60365

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location Gag(168-175)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55831

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location Gag
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Subtype B
Species (MHC/HLA) human(Cw*01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords binding affinity, immunodominance

Notes

References

Cao2008 Jianhong Cao, John McNevin, Matthew McSweyn, Yi Liu, James I. Mullins, and M. Juliana McElrath. Novel Cytotoxic T-Lymphocyte Escape Mutation by a Three-Amino-Acid Insertion in the Human Immunodeficiency Virus Type 1 p6Pol and p6Gag Late Domain Associated with Drug Resistance. J. Virol., 82(1):495-502, Jan 2008. PubMed ID: 17942528. Show all entries for this paper.


Displaying record number 61937

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location Gag
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Subtype B
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Country Germany
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Other
Keywords assay or method development

Notes

References

Stoll2015 Andrej Stoll, Silke Bergmann, Christiane Mummert, Sandra M. Mueller-Schmucker, Bernd M. Spriewald, Ellen G. Harrer, and Thomas Harrer. Identification of HLA-C Restricted, HIV-1-Specific CTL Epitopes by Peptide Induced Upregulation of HLA-C Expression. J. Immunol. Methods, 418:9-18, Mar 2015. PubMed ID: 25633660. Show all entries for this paper.


Displaying record number 1155

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24(168-175 LAI)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Subtype B
Species (MHC/HLA) human(Cw*0102)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 54146

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24(36-43 HXB2)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Subtype B
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*0201, A*2501, B*1801, B*5101, Cw*0102, Cw*1203
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, mutation acquisition, optimal epitope

Notes

References

Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.


Displaying record number 58119

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24(36-43)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Subtype B
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*0201, A*2501, B*1801, B*5101, Cw*0102, Cw*1203
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection

Notes

References

Liu2011a Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, and James I. Mullins. Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection. PLoS One, 6(1):e15639, 2011. PubMed ID: 21283794. Show all entries for this paper.


Displaying record number 59070

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24(36-43)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Subtype B
Species (MHC/HLA) human(Cw*0102)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*0201, A*2501, B*1801, B*5101, Cw*0102, Cw*1203
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords viral fitness and reversion

Notes

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 172

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24(168-175 LAI)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Subtype B
Species (MHC/HLA) human(Cw*0102, Cw1)
Immunogen  
Experimental methods  
Keywords  

References

Goulder1997f P. J. Goulder, M. Bunce, G. Luzzi, R. E. Phillips, and A. J. McMichael. Potential Underestimation of HLA-C-Restricted Cytotoxic T-Lymphocyte Responses. AIDS, 11(15):1884-1886, 1997. PubMed ID: 9412710. Show all entries for this paper.


Displaying record number 55865

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location Gag
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Subtype B, D
Species (MHC/HLA) human(Cw1)
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords subtype comparisons

Notes

References

Gudmundsdotter2008 L. Gudmundsdotter, D. Bernasconi, B. Hejdeman, E. Sandstrom, A. Alaeus, K. Lidman, B. Ensoli, B. Wahren, and S. Buttò. Cross-Clade Immune Responses to Gag p24 in Patients Infected with Different HIV-1 Subtypes and Correlation with HLA Class I and II Alleles. Vaccine, 26(40):5182-5187, 19 Sep 2008. PubMed ID: 18479789. Show all entries for this paper.


Displaying record number 55490

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL8
Subtype B
Species (MHC/HLA) human(Cw1)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Tetramer binding
Keywords superinfection

Notes

References

Streeck2008a Hendrik Streeck, Bin Li, Art F. Y. Poon, Arne Schneidewind, Adrianne D. Gladden, Karen A. Power, Demetre Daskalakis, Suzane Bazner, Rosario Zuniga, Christian Brander, Eric S. Rosenberg, Simon D. W. Frost, Marcus Altfeld, and Todd M. Allen. Immune-Driven Recombination and Loss of Control after HIV Superinfection. J. Exp. Med., 205(8):1789-1796, 4 Aug 2008. PubMed ID: 18625749. Show all entries for this paper.


Displaying record number 173

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24(168-175)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Species (MHC/HLA) human(Cw1, Cw2)
Immunogen HIV-1 infection
Experimental methods  
Keywords immunodominance

Notes

References

Betts2000 M. R. Betts, J. P. Casazza, B. A. Patterson, S. Waldrop, W. Trigona, T.-M Fu, F. Kern, L. J. Picker, and R. A. Koup. Putative Immunodominant Human Imunodeficiency Virus-Specific CD8+ T Cell Responses Cannot Be Predicted by Major Histocompatibility Complex Class I Haplotype. J. Virol., 74:9144-9151, 2000. PubMed ID: 10982361. Show all entries for this paper.


Displaying record number 60642

HXB2 Location Gag(168-175)
p24(36-43)
DNA(1291..1314)
Gag Epitope Map
Author Location p24(36-43)
Epitope VIPMFSAL Epitope Alignment
VIPMFSAL epitope logo
Epitope Name VL-8
Subtype B, C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


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