HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 8 matching records:

Displaying record number 55683

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location Gag
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Subtype A, CRF02_AG
Species (MHC/HLA) human(B53)
Immunogen HIV-1 or HIV-2 infection, HIV-2 infection
Country Gambia
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords subtype comparisons, variant cross-reactivity, HIV-2

Notes

References

Ondondo2008 Beatrice O. Ondondo, Sarah L. Rowland-Jones, Lucy Dorrell, Kevin Peterson, Matthew Cotten, Hilton Whittle, and Assan Jaye. Comprehensive Analysis of HIV Gag-Specific IFN-gamma Response in HIV-1- and HIV-2-Infected Asymptomatic Patients from a Clinical Cohort in The Gambia. Eur. J. Immunol., 38(12):3549-3560, Dec 2008. PubMed ID: 19016530. Show all entries for this paper.


Displaying record number 55688

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location Gag
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Species (MHC/HLA) human(B53)
Immunogen HIV-1 or HIV-2 infection, HIV-2 infection
Country Belgium, Senegal
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, HIV-2

Notes

References

Jennes2008 Wim Jennes, Makhtar Camara, Tandakha Dièye, Souleymane Mboup, and Luc Kestens. Higher Homologous and Lower Cross-Reactive Gag-Specific T-Cell Responses in Human Immunodeficiency Virus Type 2 (HIV-2) Than in HIV-1 Infection. J. Virol., 82(17):8619-8628, Sep 2008. PubMed ID: 18562522. Show all entries for this paper.


Displaying record number 53711

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location Gag(180-188)
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Epitope Name TPY
Subtype HIV-2
Species (MHC/HLA) human(B53)
Immunogen HIV-2 infection
Country Gambia
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Tetramer binding
Keywords characterizing CD8+ T cells, HIV-2

Notes

References

Gillespie2005a Geraldine M. A. Gillespie, Susana Pinheiro, Mohammad Sayeid-Al-Jamee, Abraham Alabi, Steve Kaye, Sehu Sabally, Ramu Sarge-Njie, Harr Njai, Ken Joof, Assan Jaye, Hilton Whittle, Sarah Rowland-Jones, and Lucy Dorrell. CD8+ T Cell Responses to Human Immunodeficiency Viruses Type 2 (HIV-2) and Type 1 (HIV-1) Gag Proteins are Distinguishable by Magnitude and Breadth but not Cellular Phenotype. Eur. J. Immunol., 35(5):1445-1453, May 2005. PubMed ID: 15832290. Show all entries for this paper.


Displaying record number 187

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location Gag(173-181)
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Subtype HIV-2
Species (MHC/HLA) human(B*53)
Immunogen HIV-2 infection
Country Gambia
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HIV-2

Notes

References

Gotch1993 F. Gotch, S. N. McAdam, and C. E. Allsopp et al. Cytotoxic T Cells in HIV-2 Seropositive Gambians. Identification of a Virus-Specific MHC-Restricted Peptide Epitope. J. Immunol., 151:3361-3369, 1993. PubMed ID: 7690804. Show all entries for this paper.


Displaying record number 188

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location Gag(173-181 HIV-2)
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Subtype HIV-2
Species (MHC/HLA) human(B*5301)
Immunogen HIV-2 infection
Experimental methods  
Keywords optimal epitope, HIV-2

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 59027

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location  
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Subtype HIV-2
Species (MHC/HLA) human(B*5301)
Immunogen HIV-2 infection
Country Guinea-Bissau
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Tetramer binding
Keywords HIV-2

Notes

References

deSilva2013 Thushan I. de Silva, Yanchun Peng, Aleksandra Leligdowicz, Irfan Zaidi, Lucy Li, Harry Griffin, Marie-Eve Blais, Tim Vincent, Mavinga Saraiva, Louis-Marie Yindom, Carla van Tienen, Philippa Easterbrook, Assan Jaye, Hilton Whittle, Tao Dong, and Sarah L. Rowland-Jones. Correlates of T-Cell-Mediated Viral Control and Phenotype of CD8+ T Cells in HIV-2, a Naturally Contained Human Retroviral Infection. Blood, 121(21):4330-4339, 23 May 2013. PubMed ID: 23558015. Show all entries for this paper.


Displaying record number 55522

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location Gag(182-190 HIV-2 ROD)
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Epitope Name TPY
Subtype HIV-2
Species (MHC/HLA) human(B*5801)
Immunogen HIV-2 infection
Patient MHC/HLA A*0101, A*2402, B*07, B*5801
Country India
Experimental methods  
Keywords escape, HIV-2

Notes

References

Kageyama2008 Seiji Kageyama, Janak K. Maniar, Dattatray G. Saple, Kei Numazaki, Takashi Kurimura, and Hiroshi Ichimura. HIV-2 Amino Acid Substitutions in Gag and Env Proteins Occurring Simultaneously with Viral Load Upsurge in a Drug-Naïve Patient. J. Infect. Chemother., 14(2):151-155, Apr 2008. PubMed ID: 18622680. Show all entries for this paper.


Displaying record number 61219

HXB2 Location Gag(180-188)
p24(48-56)
DNA(1327..1353)
Gag Epitope Map
Author Location p24
Epitope TPYDINQML Epitope Alignment
TPYDINQML epitope logo
Epitope Name TL9
Species (MHC/HLA) human
Immunogen HIV-2 infection
Patient MHC/HLA 012-006: A*03, A*23, B*35, B*53, Cw*04; 012-088: A*02, B*27, B*53, Cw*02, Cw*04; 019-010: A*33, A*68, B*53, Cw*04; 023-008: A*34, B*07, B*53, Cw*04, Cw*07; 036-018: A*03, B*35, B*53, Cw*04; 045-007: A*33, B*53, Cw*04; 082-005: A*23, A*34, B*53, Cw*04
Country France
Experimental methods CTL suppression of replication, Intracellular cytokine staining
Keywords HIV-2

Notes

References

Angin2016 Mathieu Angin, Glenn Wong, Laura Papagno, Pierre Versmisse, Annie David, Charles Bayard, Bénédicte Charmeteau-De Muylder, Amel Besseghir, Rodolphe Thiébaut, Faroudy Boufassa, Gianfranco Pancino, Delphine Sauce, Olivier Lambotte, Françoise Brun-Vézinet, Sophie Matheron, Sarah L. Rowland-Jones, Rémi Cheynier, Asier Sáez-Cirión, Victor Appay, and ANRS CO5 IMMUNOVIR-2 Study Group. Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers. J. Immunol., 197(7):2787-2795, 1 Oct 2016. PubMed ID: 27566819. Show all entries for this paper.


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