HIV molecular immunology database
Found 10 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(173-181) | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Subtype | HIV-2 | |
Species (MHC/HLA) | human(B*53) | |
Immunogen | HIV-2 infection | |
Country | Gambia | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HIV-2 |
Gotch1993 F. Gotch, S. N. McAdam, and C. E. Allsopp et al. Cytotoxic T Cells in HIV-2 Seropositive Gambians. Identification of a Virus-Specific MHC-Restricted Peptide Epitope. J. Immunol., 151:3361-3369, 1993. PubMed ID: 7690804. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(180-188) | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Epitope Name | TPY | |
Subtype | HIV-2 | |
Species (MHC/HLA) | human(B53) | |
Immunogen | HIV-2 infection | |
Country | Gambia | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Tetramer binding | |
Keywords | characterizing CD8+ T cells, HIV-2 |
Gillespie2005a Geraldine M. A. Gillespie, Susana Pinheiro, Mohammad Sayeid-Al-Jamee, Abraham Alabi, Steve Kaye, Sehu Sabally, Ramu Sarge-Njie, Harr Njai, Ken Joof, Assan Jaye, Hilton Whittle, Sarah Rowland-Jones, and Lucy Dorrell. CD8+ T Cell Responses to Human Immunodeficiency Viruses Type 2 (HIV-2) and Type 1 (HIV-1) Gag Proteins are Distinguishable by Magnitude and Breadth but not Cellular Phenotype. Eur. J. Immunol., 35(5):1445-1453, May 2005. PubMed ID: 15832290. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | Gag | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Species (MHC/HLA) | human(B53) | |
Immunogen | HIV-1 or HIV-2 infection, HIV-2 infection | |
Country | Belgium, Senegal | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | subtype comparisons, HIV-2 |
Jennes2008 Wim Jennes, Makhtar Camara, Tandakha Dièye, Souleymane Mboup, and Luc Kestens. Higher Homologous and Lower Cross-Reactive Gag-Specific T-Cell Responses in Human Immunodeficiency Virus Type 2 (HIV-2) Than in HIV-1 Infection. J. Virol., 82(17):8619-8628, Sep 2008. PubMed ID: 18562522. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | Gag | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Subtype | A, CRF02_AG | |
Species (MHC/HLA) | human(B53) | |
Immunogen | HIV-1 or HIV-2 infection, HIV-2 infection | |
Country | Gambia | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | subtype comparisons, variant cross-reactivity, HIV-2 |
Ondondo2008 Beatrice O. Ondondo, Sarah L. Rowland-Jones, Lucy Dorrell, Kevin Peterson, Matthew Cotten, Hilton Whittle, and Assan Jaye. Comprehensive Analysis of HIV Gag-Specific IFN-gamma Response in HIV-1- and HIV-2-Infected Asymptomatic Patients from a Clinical Cohort in The Gambia. Eur. J. Immunol., 38(12):3549-3560, Dec 2008. PubMed ID: 19016530. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(173-181 HIV-2) | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Subtype | HIV-2 | |
Species (MHC/HLA) | human(B*53:01) | |
Immunogen | HIV-2 infection | |
Experimental methods | ||
Keywords | optimal epitope, HIV-2, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | ||
Epitope |
TPYDINQML
|
Epitope Alignment
|
Subtype | HIV-2 | |
Species (MHC/HLA) | human(B*53:01) | |
Immunogen | HIV-2 infection | |
Country | Guinea-Bissau | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Tetramer binding | |
Keywords | HIV-2 |
deSilva2013 Thushan I. de Silva, Yanchun Peng, Aleksandra Leligdowicz, Irfan Zaidi, Lucy Li, Harry Griffin, Marie-Eve Blais, Tim Vincent, Mavinga Saraiva, Louis-Marie Yindom, Carla van Tienen, Philippa Easterbrook, Assan Jaye, Hilton Whittle, Tao Dong, and Sarah L. Rowland-Jones. Correlates of T-Cell-Mediated Viral Control and Phenotype of CD8+ T Cells in HIV-2, a Naturally Contained Human Retroviral Infection. Blood, 121(21):4330-4339, 23 May 2013. PubMed ID: 23558015. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(182-190 HIV-2 ROD) | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Epitope Name | TPY | |
Subtype | HIV-2 | |
Species (MHC/HLA) | human(B*58:01) | |
Immunogen | HIV-2 infection | |
Patient MHC/HLA | A*01:01, A*24:02, B*07, B*58:01 | |
Country | India | |
Experimental methods | ||
Keywords | escape, HIV-2 |
Kageyama2008 Seiji Kageyama, Janak K. Maniar, Dattatray G. Saple, Kei Numazaki, Takashi Kurimura, and Hiroshi Ichimura. HIV-2 Amino Acid Substitutions in Gag and Env Proteins Occurring Simultaneously with Viral Load Upsurge in a Drug-Naïve Patient. J. Infect. Chemother., 14(2):151-155, Apr 2008. PubMed ID: 18622680. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(182-190) | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Species (MHC/HLA) | human | |
Immunogen | HIV-2 infection | |
Country | Guinea-Bissau | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | HIV-2 |
deSilva2018 Thushan I. de Silva, Aleksandra Leligdowicz, Jonathan Carlson, Miguel Garcia-Knight, Clayton Onyango, Nicholas Miller, Louis-Marie Yindom, Stephane Hue, Assan Jaye, Tao Dong, Matthew Cotten, and Sarah L. Rowland-Jones. HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation. AIDS, 32(6):709-714 doi, Mar 2018. PubMed ID: 29369160 Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | p24 | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Epitope Name | TL9 | |
Species (MHC/HLA) | human | |
Immunogen | HIV-2 infection | |
Patient MHC/HLA | 012-006: A*03, A*23, B*35, B*53, C*04; 012-088: A*02, B*27, B*53, C*02, C*04; 019-010: A*33, A*68, B*53, C*04; 023-008: A*34, B*07, B*53, C*04, C*07; 036-018: A*03, B*35, B*53, C*04; 045-007: A*33, B*53, C*04; 082-005: A*23, A*34, B*53, C*04 | |
Country | France | |
Experimental methods | CTL suppression of replication, Intracellular cytokine staining | |
Keywords | HIV-2 |
Angin2016 Mathieu Angin, Glenn Wong, Laura Papagno, Pierre Versmisse, Annie David, Charles Bayard, Bénédicte Charmeteau-De Muylder, Amel Besseghir, Rodolphe Thiébaut, Faroudy Boufassa, Gianfranco Pancino, Delphine Sauce, Olivier Lambotte, Françoise Brun-Vézinet, Sophie Matheron, Sarah L. Rowland-Jones, Rémi Cheynier, Asier Sáez-Cirión, Victor Appay, and ANRS CO5 IMMUNOVIR-2 Study Group. Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers. J. Immunol., 197(7):2787-2795, 1 Oct 2016. PubMed ID: 27566819. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(180-188) p24(48-56) DNA(1327..1353) |
Gag Epitope Map |
---|---|---|
Author Location | p24(180-188) | |
Epitope |
TPYDINQML
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.