HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 59219

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HXB2 Location Nef(71-81)
DNA(9007..9039)
Nef Epitope Map
Author Location Nef(71-81)
Epitope TPQVPLRPMTY Epitope Alignment
TPQVPLRPMTY epitope logo
Epitope Name Nef 71-81
Subtype B
Species (MHC/HLA) human(B*07, B*35)
Immunogen vaccine
Country France
Experimental methods CD8 T-cell Elispot - IFNγ, Degranulation, CD107a and b cell surface mobilization, Intracellular cytokine staining, Tetramer binding
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type lipopeptide

Notes

References

Figueiredo2014 Suzanne Figueiredo, Benedicte Charmeteau, Mathieu Surenaud, Dominique Salmon, Odile Launay, Jean-Gérard Guillet, Anne Hosmalin, and Hanne Gahery. Memory CD8+ T Cells Elicited by HIV-1 Lipopeptide Vaccines Display Similar Phenotypic Profiles but Differences in Term of Magnitude and Multifunctionality Compared with FLU- or EBV-Specific Memory T Cells in Humans. Vaccine, 32(4):492-501, 16 Jan 2014. PubMed ID: 24291199. Show all entries for this paper.


Displaying record number 52127

Download this epitope record as JSON.

HXB2 Location Nef(71-81)
DNA(9007..9039)
Nef Epitope Map
Author Location Nef(71-81 BRU)
Epitope TPQVPLRPMTY Epitope Alignment
TPQVPLRPMTY epitope logo
Subtype B
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords binding affinity, epitope processing

Notes

References

Choppin2001 Jeannine Choppin, William Cohen, Albert Bianco, Jean-Paul Briand, Francine Connan, Marc Dalod, and Jean-Gérard Guillet. Characteristics of HIV-1 Nef Regions Containing Multiple CD8+ T Cell Epitopes: Wealth of HLA-Binding Motifs and Sensitivity to Proteasome Degradation. J. Immunol., 166(10):6164-6169, 15 May 2001. PubMed ID: 11342637. Show all entries for this paper.


Displaying record number 52126

Download this epitope record as JSON.

HXB2 Location Nef(71-81)
DNA(9007..9039)
Nef Epitope Map
Author Location Nef(71-81 BRU)
Epitope TPQVPLRPMTY Epitope Alignment
TPQVPLRPMTY epitope logo
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods  
Keywords binding affinity, epitope processing

Notes

References

Choppin2001 Jeannine Choppin, William Cohen, Albert Bianco, Jean-Paul Briand, Francine Connan, Marc Dalod, and Jean-Gérard Guillet. Characteristics of HIV-1 Nef Regions Containing Multiple CD8+ T Cell Epitopes: Wealth of HLA-Binding Motifs and Sensitivity to Proteasome Degradation. J. Immunol., 166(10):6164-6169, 15 May 2001. PubMed ID: 11342637. Show all entries for this paper.


Displaying record number 52960

Download this epitope record as JSON.

HXB2 Location Nef(71-81)
DNA(9007..9039)
Nef Epitope Map
Author Location Nef(71-81)
Epitope TPQVPLRPMTY Epitope Alignment
TPQVPLRPMTY epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B7 supertype)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Proliferation
Keywords vaccine-induced immune responses, variant cross-reactivity

Vaccine Details

Vaccine type lipopeptide
Vaccine strain B clade LAI
Vaccine component Env, Gag, Nef
Adjuvant QS21

Notes

References

Gahery-Segard2003 Hanne Gahéry-Ségard, Gilles Pialoux, Suzanne Figueiredo, Céline Igéa, Mathieu Surenaud, Jessintha Gaston, Helene Gras-Masse, Jean-Paul Lévy, and Jean-Gérard Guillet. Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8+-T-Cell Epitopes Recognized. J. Virol., 77(20):11220-11231, Oct 2003. PubMed ID: 14512570. Show all entries for this paper.


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