HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 61184

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HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef(128-137)
Epitope TPGPGTRYPL Epitope Alignment
TPGPGTRYPL epitope logo
Show epitope variants
Epitope Name TTL10
Subtype B
Species (MHC/HLA) human(B*07:02)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords acute/early infection, variant cross-reactivity

Notes

References

Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.


Displaying record number 54545

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HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef(128-137)
Epitope TPGPGTRYPL Epitope Alignment
TPGPGTRYPL epitope logo
Show epitope variants
Epitope Name TL10
Subtype B
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection, assay or method development, mutation acquisition

Notes

References

Malhotra2007a Uma Malhotra, Fusheng Li, Jessica Nolin, Megan Allison, Hong Zhao, James I. Mullins, Steve Self, and M. Juliana McElrath. Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection. J. Virol., 81(10):5225-5237, May 2007. PubMed ID: 17329342. Show all entries for this paper.


Displaying record number 59251

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef(128-137)
Epitope TPGPGTRYPL Epitope Alignment
TPGPGTRYPL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA Subject 8: A*02:01, A*24:02, B*07:02, B*40:01, C*03:04, C*07:02
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords dynamics, acute/early infection, dendritic cells

Notes

References

Melhem2014 Nada M Melhem, Kellie N. Smith, Xiao-Li Huang, Bonnie A Colleton, Weimin Jiang, Robbie B. Mailliard, James I. Mullins, and Charles R. Rinaldo. The Impact of Viral Evolution and Frequency of Variant Epitopes on Primary and Memory Human Immunodeficiency Virus Type 1-Specific CD8+ T Cell Responses. Virology, 450-451:34-48, Feb 2014. PubMed ID: 24503065. Show all entries for this paper.


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