HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 7 matching records:

Displaying record number 59047

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef
Epitope TPGPGIRYPL Epitope Alignment
TPGPGIRYPL epitope logo
Show epitope variants
Epitope Name TL10-Nef
Subtype B
Species (MHC/HLA) human(B*07:02)
Immunogen HIV-1 infection
Country Japan, South Africa, United Kingdom, United States
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, subtype comparisons

Notes

References

Kloverpris2014 Henrik N. Kløverpris, Emily Adland, Madoka Koyanagi, Anette Stryhn, Mikkel Harndahl, Philippa C. Matthews, Roger Shapiro, Bruce D. Walker, Thumbi Ndung'u, Christian Brander, Masafumi Takiguchi, Søren Buus, and Philip Goulder. HIV Subtype Influences HLA-B*07:02-Associated HIV Disease Outcome. AIDS Res. Hum. Retroviruses, 30(5):468-475, May 2014. PubMed ID: 24010680. Show all entries for this paper.


Displaying record number 61160

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef(128-137)
Epitope TPGPGIRYPL Epitope Alignment
TPGPGIRYPL epitope logo
Show epitope variants
Epitope Name TL10
Subtype B
Species (MHC/HLA) human(B*07:02)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords acute/early infection, variant cross-reactivity

Notes

References

Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.


Displaying record number 57958

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef(128-137)
Epitope TPGPGIRYPL Epitope Alignment
TPGPGIRYPL epitope logo
Show epitope variants
Epitope Name TL10
Subtype B
Species (MHC/HLA) human(B*07:02)
Immunogen HIV-1 infection
Country Australia
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords escape, HLA associated polymorphism

Notes

References

Keane2012 Niamh M. Keane, Steven G. Roberts, Coral-Ann M. Almeida, Tanya Krishnan, Abha Chopra, Emma Demaine, Rebecca Laird, Monika Tschochner, Jonathan M. Carlson, Simon Mallal, David Heckerman, Ian James, and Mina John. High-Avidity, High-IFN-gamma-Producing CD8 T-Cell Responses following Immune Selection during HIV-1 Infection. Immunol. Cell Biol., 90(2):224-234, Feb 2012. PubMed ID: 21577229. Show all entries for this paper.


Displaying record number 57224

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef
Epitope TPGPGIRYPL Epitope Alignment
TPGPGIRYPL epitope logo
Species (MHC/HLA) human(B42)
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords mother-to-infant transmission

Notes

References

Lohman-Payne2009 B. Lohman-Payne, J. A. Slyker, B. A. Richardson, C. Farquhar, M. Majiwa, E. Maleche-Obimbo, D. Mbori-Ngacha, J. Overbaugh, S. Rowland-Jones, and G. John-Stewart. Infants with Late Breast Milk Acquisition of HIV-1 Generate Interferon-gamma Responses More Rapidly than Infants with Early Peripartum Acquisition. Clin. Exp. Immunol., 156(3):511-517, Jun 2009. PubMed ID: 19438605. Show all entries for this paper.


Displaying record number 56094

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef
Epitope TPGPGIRYPL Epitope Alignment
TPGPGIRYPL epitope logo
Epitope Name Nef1133
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, computational epitope prediction, HLA associated polymorphism

Notes

References

DeGroot2008 Anne S. De Groot, Daniel S. Rivera, Julie A. McMurry, Soren Buus, and William Martin. Identification of Immunogenic HLA-B7 ``Achilles' Heel'' Epitopes within Highly Conserved Regions of HIV. Vaccine, 26(24):3059-3071, 6 Jun 2008. PubMed ID: 18206276. Show all entries for this paper.


Displaying record number 57502

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef
Epitope TPGPGIRYPL Epitope Alignment
TPGPGIRYPL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Australia
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords assay or method development, HLA associated polymorphism, chronic infection

Notes

References

Almeida2010 Coral-Ann M. Almeida, Steven G. Roberts, Rebecca Laird, Elizabeth McKinnon, Imran Ahmad, Niamh M. Keane, Abha Chopra, Carl Kadie, David Heckerman, Simon Mallal, and Mina John. Exploiting Knowledge of Immune Selection in HIV-1 to Detect HIV-Specific CD8 T-Cell Responses. Vaccine, 28(37):6052-6057, 23 Aug 2010. PubMed ID: 20619380. Show all entries for this paper.


Displaying record number 1324

Download this epitope record as JSON.

HXB2 Location Nef(128-137)
DNA(9178..9207)
Nef Epitope Map
Author Location Nef
Epitope TPGPGIRYPL Epitope Alignment
TPGPGIRYPL epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001 R. Kaul, S. L. Rowland-Jones, J. Kimani, T. Dong, H. B. Yang, P. Kiama, T. Rostron, E. Njagi, J. J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Late Seroconversion in HIV-Resistant Nairobi Prostitutes Despite Pre-Existing HIV-Specific CD8+ Responses. J. Clin. Invest., 107(3):341-349, Feb 2001. URL: http://www.jci.org/cgi/content/full/107/3/341. PubMed ID: 11160158. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health